94112-85-3

Basic information

• Product Name: 4-Oxo-4-(3'-isopropyl-4'-methoxyphenyl)butyric acid
• Synonyms: 4-Oxo-4-(3'-isopropyl-4'-methoxyphenyl)butyric acid
• CAS NO: 94112-85-3
• Molecular Weight: 250.295
• Mol File: 94112-85-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-Oxo-4-(3'-isopropyl-4'-methoxyphenyl)butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Oxo-4-(3'-isopropyl-4'-methoxyphenyl)butyric acid(94112-85-3)
• EPA Substance Registry System: 4-Oxo-4-(3'-isopropyl-4'-methoxyphenyl)butyric acid(94112-85-3)

Safety Data

• Hazardous Substances Data: 94112-85-3(Hazardous Substances Data)

Upstream product

• 106165-94-0 4-(4-hydroxy-3-isopropyl-phenyl)-4-oxo-butyric acid 
• 77-78-1 dimethyl sulfate 
• 88-69-7 2-(1-methylethyl)phenol 
• 1025911-50-5 4-(3-Isopropyl-4-methoxy-phenyl)-4-oxo-butyric acid ethyl ester 
• 2944-47-0 o-isopropylanisole 
• 108-30-5 succinic acid anhydride 

Downstream Products

• 39863-61-1 4-(3'-Isopropyl-4'-methoxyphenyl)butyric acid 
• 27210-57-7 miltirone 
• 116064-77-8 1,2-didehydromiltirone 
• 1026392-96-0 4-[Hydroxy-(7-isopropoxy-6-isopropyl-1-oxo-1,2,3,4-tetrahydro-naphthalen-2-yl)-methyl]-benzoic acid methyl ester 
• 1027933-81-8 4-[Hydroxy-(6-isopropyl-7-methoxy-1-oxo-1,2,3,4-tetrahydro-naphthalen-2-yl)-methyl]-benzoic acid methyl ester 
• 1026632-48-3 4-[6-Isopropyl-7-methoxy-1-oxo-3,4-dihydro-1H-naphthalen-(2E)-ylidenemethyl]-benzoic acid methyl ester 
• 1026404-82-9 4-(3-Isopropyl-4-methoxy-phenyl)-butyryl chloride 
• 22009-41-2 6-isopropyl-7-methoxy-3,4-dihydronaphthalen-1(2H)-one 
• 109512-98-3 4-(3-isopropyl-4-methoxy-phenyl)-butyric acid methyl ester 
• 33537-78-9 4-Methoxy-3-isopropylbenzoic acid 

Relevant articles and documents

Structure Elucidation and Total Synthesis of New Tanshinones Isolated from Salvia miltiorrhiza Bunge (Danshen)

Totally 11 new compounds have been isolated from the dried root of Salvia miltiorrhiza Bunge "Danshen" and their structures were elucidated by means of spectrometric methods.The total syntheses of two new compounds, namely, 1,2-didehydromiltirone and 4-methylenemiltirone, are also reported.

A novel type of retinoic acid receptor antagonist: Synthesis and structure-activity relationships of heterocyclic ring-containing benzoic acid derivatives

A new series of heterocyclic ring-containing benzoic acids was prepared, and the binding affinity and antagonism of its members against all-trans- retinoic acid were evaluated by in vitro assay systems using human promyelocytic leukemia (HL-60) cells. Structure-activity relationships indicated that both an N-substituted pyrrole or pyrazole (1-position) and a hydrophobic region, with these linked by a ring system, were indispensable for effective antagonism. Among the compounds evaluated, optimal antagonism was exhibited by 4-[4,5,7,8,9,10-hexahydro-7,7,10,-10-tetramethyl-1-(3- pyridylmethyl)anthra[1,2-b]pyrrol-3-yl]benzoic acid (31), 4-[4,5,7,8,9,10- hexahydro-7,7,10,10-tetramethyl-1-(3-pyridylmethyl)-5-thiaanthra[1,2- b]pyrrol-3-yl]benzoic acid (40), and 4-[4,5,7,8,9,10-hexahydro-7,7,10,10- tetramethyl-1-(3-pyridylmethyl)anthra[2,1-d]pyrazol-3-yl]benzoic acid (55), all of which possess a 3-pyridylmethyl group at the five-membered ring nitrogen atom.