941294-26-4 Usage
General Description
3-Chloro-6-(4-methyl-1H-imidazol-1-yl)pyridazine is a chemical compound with the molecular formula C8H6ClN5. It is a pyridazine derivative with a chlorine atom and an imidazole ring attached to the pyridazine ring. 3-Chloro-6-(4-methyl-1H-imidazol-1-yl)pyridazine has potential applications in pharmaceutical research and development due to its unique structure and potential biological activities. However, further studies are needed to fully understand its properties and potential uses in various fields such as medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 941294-26-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,1,2,9 and 4 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 941294-26:
(8*9)+(7*4)+(6*1)+(5*2)+(4*9)+(3*4)+(2*2)+(1*6)=174
174 % 10 = 4
So 941294-26-4 is a valid CAS Registry Number.
941294-26-4Relevant articles and documents
4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable stearoyl-CoA desaturase-1 (SCD1) inhibitors: Part 2. Pyridazine-based analogs
Yang, Shyh-Ming,Tang, Yuting,Rano, Thomas,Lu, Huajun,Kuo, Gee-Hong,Gaul, Michael D.,Li, Yaxin,Ho, George,Lang, Wensheng,Conway, James G.,Liang, Yin,Lenhard, James M.,Demarest, Keith T.,Murray, William V.
, p. 1437 - 1441 (2014)
Design, synthesis, and biological evaluation of pyridazine-based, 4-bicyclic heteroaryl-piperidine derivatives as potent stearoyl-CoA desaturase-1 (SCD1) inhibitors are described. In a chronic study of selected analog (3e) in Zucker fa/fa (ZF) rat, dose-dependent decrease of body weight gain and plasma fatty acid desaturation index (DI) in both C16 and C18 are also demonstrated. The results indicate that the plasma fatty acid DI may serve as an indicator for direct target engagement and biomarker for SCD1 inhibition.
