941587-76-4Relevant articles and documents
Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 1. Newly generated antibacterial activities against Gram-positive bacteria with erm gene by C-7 modification
Wakiyama, Yoshinari,Kumura, Ko,Umemura, Eijiro,Ueda, Kazutaka,Masaki, Satomi,Kumura, Megumi,Fushimi, Hideki,Ajito, Keiichi
, p. 368 - 380 (2016/06/09)
We synthesized 7(S)-7-deoxy-7-arylthiolincomycin derivatives possessing a heterocyclic ring at the C-7 position via sulfur atom by either Mitsunobu reaction of 2,3,4-tris-O-(trimethylsiliyl)lincomycin or S N 2 reaction of 7-O-methanesulfonyl-2,3,4-tri-O-t