941602-99-9

Basic information

• Product Name: 3-[(2,6-dichloro-3-fluorophenyl)methoxy]-2-nitropyridine
• Synonyms: 3-[(2,6-dichloro-3-fluorophenyl)methoxy]-2-nitropyridine
• CAS NO: 941602-99-9
• Molecular Weight: 317.104
• Mol File: 941602-99-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-[(2,6-dichloro-3-fluorophenyl)methoxy]-2-nitropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(2,6-dichloro-3-fluorophenyl)methoxy]-2-nitropyridine(941602-99-9)
• EPA Substance Registry System: 3-[(2,6-dichloro-3-fluorophenyl)methoxy]-2-nitropyridine(941602-99-9)

Safety Data

• Hazardous Substances Data: 941602-99-9(Hazardous Substances Data)

Upstream product

• 290835-85-7 2',6'-dichloro-3'-fluoroacetophenone 
• 15128-82-2 3-hydroxy-2-nitropyridine 
• 1227611-90-6 (2,6-dichloro-3-fluorophenyl)methanol 
• 756520-66-8 1-(2,6-dichloro-3-fluorophenyl)ethanol 

Downstream Products

• 941603-00-5 3-[(2,6-dichloro-3-fluorophenyl)methoxy]pyridin-2-amine 

Relevant articles and documents

CRIZOTINIB FOR USE IN THE TREATMENT OF CANCER

The present invention relates to the use of ROS kinase inhibitors for treating abnormal cell growth in mammals. In particular, the invention provides methods of treating mammals suffering from cancer mediated by at least one genetically altered ROS. In particular, the invention provides methods of treating mammals suffering from cancer mediated by at least one genetically altered ROS by administration of crizotinib.

Method of Treating Abnormal Cell Growth

The present invention relates to the use of (R)-3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine, a novel c-Met/HGFR inhibitor, for treating abnormal cell growth in mammals. In particular, the invention provides methods of treating mammals suffering from cancer.