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941685-08-1

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941685-08-1 Usage

Structure

Bromo-substituted pyrrolopyridine derivative

Contains

A trimethylsilyl group and an ethoxymethyl group

Usage

Building block or intermediate for the synthesis of various pharmaceuticals and bioactive molecules

Value

Unique structure and reactivity for the creation of diverse molecular structures with potential biological activities.

Check Digit Verification of cas no

The CAS Registry Mumber 941685-08-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,1,6,8 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 941685-08:
(8*9)+(7*4)+(6*1)+(5*6)+(4*8)+(3*5)+(2*0)+(1*8)=191
191 % 10 = 1
So 941685-08-1 is a valid CAS Registry Number.

941685-08-1Relevant articles and documents

PYRIDO-OXAZINE DERIVATIVES AS ALK5 INHIBITORS

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Page/Page column 76-77, (2022/01/24)

The present invention relates to a compound of general formula (I) inhibiting the growth factor receptor transforming β (TGF-β) type I (ALK5), methods for preparing such compounds, pharmaceutical compositions containing them and their therapeutic use. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of the ALK5 signaling pathway in a mammal.

COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF

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Paragraph 0070-0071, (2021/10/30)

The present invention relates to novel Collagen 1 translation inhibitors, composition and methods of preparation thereof, and uses thereof for treating Fibrosis including lung, liver, kidney, cardiac and dermal fibrosis, IPF, wound healing, scarring and Gingival fibromatosis, Systemic Sclerosis, and alcoholic and non-alcoholic steatohepatitis (NASH).

TYROSINE ANALOGUES DERIVATIVES AS RHO- KINASE INHIBITORS

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Page/Page column 56, (2019/04/09)

The invention relates to compounds of formula (I) inhibiting Rho Kinase that are tyrosine analogues derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. Particularly the compounds of the invention may be useful in the treatment of many disorders associated with ROCK enzymes mechanisms, such as pulmonary diseases including asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).

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