94220-38-9

Basic information

• Product Name: 7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE
• Synonyms: 7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE;1H-Pyrazolo[4,3-b]pyridine, 7-chloro-5-Methyl-
• CAS NO: 94220-38-9
• Molecular Formula: C₇H₆ClN₃
• Molecular Weight: 167.6
• Mol File: 94220-38-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 307.317 °C at 760 mmHg
• Flash Point: 168.442 °C
• Appearance: /
• Density: 1.438 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.688
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE(94220-38-9)
• EPA Substance Registry System: 7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE(94220-38-9)

Safety Data

• Hazardous Substances Data: 94220-38-9(Hazardous Substances Data)

Usage

General Description

7-Chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine is a chemical compound with the molecular formula C8H6ClN3. It is a heterocyclic compound that belongs to the pyrazolo[4,3-b]pyridine family. This chemical is used in the pharmaceutical industry as a building block for the synthesis of various pharmaceutical compounds, particularly those with potential therapeutic applications. It possesses a unique structure that makes it a valuable intermediate for the development of new drugs. Additionally, it can also be used as a research tool in the study of chemical reactions and biological processes. Overall, 7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine has significant importance in medicinal chemistry and chemical research.

InChI:InChI=1/C7H6ClN3/c1-4-2-5(8)7-6(10-4)3-9-11-7/h2-3H,1H3,(H,9,11)

Upstream product

• 268547-52-0 5-methyl-1H-pyrazolo[4,3-b]pyridine-7-ol 
• 95-14-7 1,2,3-Benzotriazole 

Downstream Products

• 268547-53-1 3-bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine 
• 866141-78-8 1-[4-(6-cyclopropylmethyl-7-ethyl-4-methyl-7,8-dihydro-6H-1,3,6,8a-tetraaza-acenaphthylen-2-yl)-3-trifluoromethyl-phenyl]-ethanone 
• 866141-79-9 6-cyclopropylmethyl-7-ethyl-2-(4-isopropenyl-2-trifluoromethyl-phenyl)-4-methyl-7,8-dihydro-6H-1,3,6,8a-tetraaza-acenaphthylene 

Relevant articles and documents

CRF RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO

CRF receptor antagonists are disclosed which may have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in a mammals, such as stroke. The CRF receptor antagonists of this invention have the following structure: and pharmaceutically acceptable salts, esters, solvates, stereoisomers and prodrugs thereof, wherein R1, R2n, R5, Ar, and Het are as defined herein. Compositions containing a CRF receptor antagonist in combination with a pharmaceutically acceptable carrier are also disclosed, as well as methods for use of the same.

CRF receptor antagonists and methods relating thereto

CRF receptor antagonists are disclosed which have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in a warm-blooded animals, such as stroke. The CRF receptor antagonists of this invention have the following structure: including stereoisomers and pharmaceutically acceptable salts thereof, wherein n, m, A, B, C, R, R1, R2and Ar are as defined herein. Compositions containing a CRF receptor antagonist in combination with a pharmaceutically acceptable carrier are also disclosed, as well as methods for use of the same