942271-27-4

Basic information

• Product Name: C₂₃H₂₇F₃N₂O₃
• Synonyms: C₂₃H₂₇F₃N₂O₃
• CAS NO: 942271-27-4
• Molecular Weight: 436.474
• Mol File: 942271-27-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₇F₃N₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₇F₃N₂O₃(942271-27-4)
• EPA Substance Registry System: C₂₃H₂₇F₃N₂O₃(942271-27-4)

Safety Data

• Hazardous Substances Data: 942271-27-4(Hazardous Substances Data)

Upstream product

• 58551-83-0 2,4,6-trifluorobenzaldehyde 
• 138227-63-1 tert-butyl 4-(4-aminophenoxy)piperidine-1-carboxylate 

Downstream Products

• 942271-29-6 C₁₈H₁₉F₃N₂O 

Relevant articles and documents

Substituted aniline derivatives useful as histamine H3 antagonists

Disclosed are compounds of the formula or a pharmaceutically acceptable salt thereof, wherein M1 is M2 is N; X is a bond, optionally substituted alkylene, alkenylene, —O—, —CH2N(R12)—, —N(R12)CH2—, —N(R12)—, —NHC(O)—, —OCH2—, —CH2O—, or —S(O)0-2—; and Y is —(CH2)1-2—, —C(═O)—, —C(═NOR13)— or —SO0-2—; or M1 is N; M2 is N or CH; X is a bond, alkylene, alkenylene, —C(O)—, —NHC(O)—, —OC(O)— or —S(O)1-2—; Y is —(CH2)1-2—, —C(═O)— or —SO0-2—; and when M2 is CH, Y is also Y is —O— or —C(═NOR13)—; Z is a bond or optionally substituted alkylene or alkenylene; U and W are CH, or one is CH and one is N; R1 is optionally substituted alkyl, cycloalkyl, aryl, arylalkyl, heteroaryl, heterocycloalkyl; R2 is optionally substituted alkyl, alkenyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, cycloalkyl or heterocycloalkyl; and the remaining variables are as defined in the specification; and compositions and methods of treating obesity, metabolic syndrome and a cognition deficit disorder, alone or in combination with other agents.