942274-97-7

Basic information

• Product Name: methyl 2-(3-acetylpyridin-2-yl)benzoate
• Synonyms: methyl 2-(3-acetylpyridin-2-yl)benzoate
• CAS NO: 942274-97-7
• Molecular Weight: 255.273
• Mol File: 942274-97-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-(3-acetylpyridin-2-yl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(3-acetylpyridin-2-yl)benzoate(942274-97-7)
• EPA Substance Registry System: methyl 2-(3-acetylpyridin-2-yl)benzoate(942274-97-7)

Safety Data

• Hazardous Substances Data: 942274-97-7(Hazardous Substances Data)

Upstream product

• 84199-61-1 1-(2′-bromo-3′-pyridyl)ethan-1-one 
• 374538-03-1 2-methoxycarbonylphenylboronic acid 
• 55676-21-6 3-acetyl-2-chloropyridine 
• 653589-95-8 2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzoic acid methyl ester 

Relevant articles and documents

Asymmetric Reductive Amination/Ring-Closing Cascade: Direct Synthesis of Enantioenriched Biaryl-Bridged NH Lactams

We report here a Ru-catalyzed enantioselective synthesis of biaryl-bridged NH lactams through asymmetric reductive amination and a spontaneous ring-closing cascade from keto esters and NH4OAc with H2 as reductant. The reaction features broad substrate generality and high enantioselectivities (up to >99percent ee). To showcase the practical utility, a highly enantioselective synthesis of 5-ethylindolobenzazepinone C, a promising antimitotic agent, has been rapidly completed. Furthermore, the amide group in the products enables versatile elaborations through directed C-H functionalization.