942408-19-7Relevant articles and documents
SAR studies on thiazolo[4,5-d]pyrimidine based CXCR2 antagonists involving a novel tandem displacement reaction
Hunt, Fraser,Austin, Caroline,Austin, Rupert,Bonnert, Roger,Cage, Peter,Christie, Jadeen,Christie, Mark,Dixon, Clare,Hill, Steven,Jewell, Robert,Martin, Ian,Robinson, David,Willis, Paul
, p. 2731 - 2734 (2008/02/07)
As part of a Lead Optimisation programme to identify small molecule antagonists of the human CXCR2 receptor, a series of substituted thiazolo[4,5-d]pyrimidines was prepared via the application of a novel tandem displacement reaction.