94242-82-7

Basic information

• Product Name: 1,3,2-Dioxaborolane, 2-(1-chloro-2-phenylethyl)-4,4,5,5-tetramethyl-
• CAS NO: 94242-82-7
• Molecular Formula: C14H20BClO2
• Molecular Weight: 266.576
• Mol File: 94242-82-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,3,2-Dioxaborolane, 2-(1-chloro-2-phenylethyl)-4,4,5,5-tetramethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,2-Dioxaborolane, 2-(1-chloro-2-phenylethyl)-4,4,5,5-tetramethyl-(94242-82-7)
• EPA Substance Registry System: 1,3,2-Dioxaborolane, 2-(1-chloro-2-phenylethyl)-4,4,5,5-tetramethyl-(94242-82-7)

Safety Data

• Hazardous Substances Data: 94242-82-7(Hazardous Substances Data)

Upstream product

• 2146-67-0 (dichloromethyl)lithium 
• 87100-28-5 pinacol benzylboronate 
• 75-09-2 dichloromethane 
• 1259299-79-0 2-(1-chloro-2-phenylvinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1333-74-0 hydrogen 
• 159087-45-3 4,4,5,5-tetramethyl-2-phenylethynyl-[1,3,2]dioxaborolane 
• 536-74-3 phenylacetylene 
• 61676-62-8 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 83622-41-7 pinacol dichloromethylboronic ester 
• 6921-34-2 benzylmagnesium chloride 
• 162213-35-6 C₁₃H₂₁BO₂ 
• 1589-82-8 phenylmagnesium bromide 
• 4463-42-7 benzyl boronic acid 
• 76-09-5 2,3-dimethyl-2,3-butane diol 

Downstream Products

• 94242-83-8 2-[1-(1,1,1,3,3,3-hexamethyl-disilazan-2-yl)-2-phenyl-ethyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 
• 97571-08-9 2-(3,3-dimethyl-1-phenylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant articles and documents

Ni-Catalyzed Reductive Allylation of α-Chloroboronates to Access Homoallylic Boronates

The transition-metal-catalyzed allylation reaction is an efficient strategy for the construction of new carbon-carbon bonds alongside allyl or homoallylic functionalization. Herein we describe a Ni-catalyzed reductive allylation of α-chloroboronates to efficiently render the corresponding homoallylic boronates, which could be readily converted into valuable homoallylic alcohols or amines or 1,4-diboronates. This reaction features a broad substrate scope with good functional group compatibility that is complementary to the existing methods for the preparation of homoallylic boronates.

P1 Phenethyl peptide boronic acid inhibitors of HCV NS3 protease

A series of peptide boronic acids containing extended, hydrophobic P1 residues was prepared to probe the shallow, hydrophobic S1 region of HCV NS3 protease. The p-trifluoromethylphenethyl P1 substituent was identified as optimal with respect to inhibitor potency for NS3 and selectivity against elastase and chymotrypsin.

ALPHA-AMINOBORONIC ACID DERIVATIVES

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