943025-77-2

Basic information

• Product Name: [(4R/S)-3-fluoro-4-hydroxy-7-oxo-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-4-yl]methyl 4-methylbenzenesulfonate
• Synonyms: [(4R/S)-3-fluoro-4-hydroxy-7-oxo-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-4-yl]methyl 4-methylbenzenesulfonate
• CAS NO: 943025-77-2
• Molecular Weight: 390.392
• Mol File: 943025-77-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [(4R/S)-3-fluoro-4-hydroxy-7-oxo-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-4-yl]methyl 4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: [(4R/S)-3-fluoro-4-hydroxy-7-oxo-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-4-yl]methyl 4-methylbenzenesulfonate(943025-77-2)
• EPA Substance Registry System: [(4R/S)-3-fluoro-4-hydroxy-7-oxo-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-4-yl]methyl 4-methylbenzenesulfonate(943025-77-2)

Safety Data

• Hazardous Substances Data: 943025-77-2(Hazardous Substances Data)

Upstream product

• 943025-72-7 3-fluoro-4-methylidene-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-7-one 
• 943025-70-5 8-[1-(chloromethyl)ethenyl]-7-fluoro-2-(methyloxy)-1,5-naphthyridine 
• 943025-69-2 7-fluoro-8-(1-methylethenyl)-2-(methyloxy)-1,5-naphthyridine 
• 724788-70-9 8-bromo-7-fluoro-2-methoxy-1,5-naphthyridine 
• 943025-64-7 (4R/S)-3-fluoro-4-hydroxy-4-(hydroxymethyl)-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-7-one 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

Novel hydroxyl tricyclics (e.g., GSK966587) as potent inhibitors of bacterial type IIA topoisomerases

During the course of our research to find novel mode of action antibacterials, we discovered a series of hydroxyl tricyclic compounds that showed good potency against Gram-positive and Gram-negative pathogens. These compounds inhibit bacterial type IIA to