943320-50-1

Basic information

• Product Name: BenzaMide, 3-iodo-4-Methyl-N-[4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)phenyl]-
• Synonyms: BenzaMide, 3-iodo-4-Methyl-N-[4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)phenyl]-;3-iodo-4-Methyl-N-(4-((4-Methylpiperazin-1-yl)Methyl)-3-(trifluoroMethyl)phenyl)benzaMide;3-Iodo-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide;N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
• CAS NO: 943320-50-1
• Molecular Formula: C21H23F3IN3O
• Molecular Weight: 517.3264996
• Mol File: 943320-50-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 466.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.532±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 12.42±0.70(Predicted)
• CAS DataBase Reference: BenzaMide, 3-iodo-4-Methyl-N-[4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: BenzaMide, 3-iodo-4-Methyl-N-[4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)phenyl]-(943320-50-1)
• EPA Substance Registry System: BenzaMide, 3-iodo-4-Methyl-N-[4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)phenyl]-(943320-50-1)

Safety Data

• Hazardous Substances Data: 943320-50-1(Hazardous Substances Data)

Usage

Description

BenzaMide, 3-iodo-4-Methyl-N-[4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)phenyl]is a complex organic compound with a unique chemical structure. It is characterized by the presence of an amide group, a benzene ring, and various substituents, including an iodine atom, a methyl group, and a trifluoromethyl group. BenzaMide, 3-iodo-4-Methyl-N-[4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)phenyl]is primarily used as a research chemical, providing valuable insights into the properties and potential applications of similar compounds.

Uses

Used in Research Applications:
BenzaMide, 3-iodo-4-Methyl-N-[4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)phenyl]is used as a research chemical compound for various scientific investigations. Its unique structure and properties make it a valuable tool for studying the interactions between molecules and their potential applications in different fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, BenzaMide, 3-iodo-4-Methyl-N-[4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)phenyl]is used as a starting material or intermediate in the synthesis of new drugs. Its chemical structure can be modified to create novel compounds with potential therapeutic effects, making it an important component in drug discovery and development.
Used in Chemical Synthesis:
BenzaMide, 3-iodo-4-Methyl-N-[4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)phenyl]is also used in chemical synthesis for the production of other organic compounds. Its versatile structure allows for various chemical reactions, enabling the creation of a wide range of products with different applications.

Upstream product

• 320-37-6 4-nitro-2-(trifluoromethyl)benzoic acid 
• 447-61-0 2-Trifluoromethylbenzaldehyde 
• 50551-17-2 4-nitro-2-(trifluoromethyl)benzaldehyde 

Downstream Products

• 943319-70-8 ponatinib 

Relevant articles and documents

Inhibitors to Overcome Secondary Mutations in the Stem Cell Factor Receptor KIT

In modern cancer therapy, the use of small organic molecules against receptor tyrosine kinases (RTKs) has been shown to be a valuable strategy. The association of cancer cells with dysregulated signaling pathways linked to RTKs represents a key element in

Benzamide compounds containing acetenyl group

The invention provides acetenyl group-containing benzamide compounds as shown in a formula (I) and used for treating or preventing diseases related to protein kinase, and medicinal salts or configurational isomers thereof. A connection group L, a ring A and substituents R, R, R, R and R in the formula (I) are as defined in the specification. The invention also discloses a preparation method and a pharmaceutical composition of the compounds as shown in the formula (I), and application of the compounds to preparation or prevention of drugs used for preventing diseases related to protein kinase.

PROTEIN KINASE INHIBITORS (VARIANTS), USE THEREOF IN TREATING ONCOLOGICAL DISEASES AND A PHARMACEUTICAL COMPOSITION BASED THEREON

The present invention relates to the treatment of oncological, chronic inflammatory and similar diseases with the aid of new families of chemical compounds having improved efficiency with regard to the inhibition of Abl kinase and mutant forms thereof, as well as other therapeutically significant kinases. It describes protein kinase inhibitors in the form of compounds of general formula (I) and compounds of general formula (II), or a tautomer, an individual isomer, a mixture of isomers, a pharmaceutically acceptable salt, a solvate or a hydrate thereof.