943320-53-4Relevant articles and documents
NEW COMPOUNDS AND METHODS
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Page/Page column 46, (2021/01/23)
The present invention relates to compounds of Formula (I) or a pharmaceutically acceptable salt, solvate, hydrate, tautomer, optical isomer, N-oxide, and/or prodrug thereof. The present invention also relates to pharmaceutical compositions comprising the compounds of the invention, and to their use in the treatment or prevention of medical conditions in which inhibition of c-ABL is beneficial. (I)
Deuterated acetylene derivatives, its pharmaceutical composition and application
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Paragraph 0137; 0139; 0144; 0145, (2018/11/22)
The invention discloses a deuterated acetylenic derivative, a pharmaceutical composition and application thereof. The deuterated acetylenic derivative comprises one or more of the deuterated acetylenic derivative (I) with curative effective dose, pharmace
Anti-tumor activity with acetylene derivatives
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Paragraph 0241-0242; 0247-0248, (2016/10/08)
The present invention relates to an aromatic ring disubstituted acetylene derivative of formula I, a pharmaceutical composition comprising the compound, and a use of the compound and of the pharmaceutical composition in the treatment and/or prevention of tumors, where A, B, T, M, Ra, Rb, Rt, m, n, and p are as defined in the present document.