943320-61-4

Basic information

• Product Name: 3-Ethynylimidazo[1,2-b]pyridazine
• Synonyms: 3-Ethynylimidazo[1,2-b]pyridazine;IMidazo[1,2-b]pyridazine, 3-ethynyl-;3-Ethynylimidazolo[1,2-b]pyridazine
• CAS NO: 943320-61-4
• Molecular Formula: C8H5N3
• Molecular Weight: 143.1454
• Mol File: 943320-61-4.mol
• Article Data: 20

Chemical Properties

• Appearance: /
• Density: 1.15±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 3.71±0.30(Predicted)
• CAS DataBase Reference: 3-Ethynylimidazo[1,2-b]pyridazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Ethynylimidazo[1,2-b]pyridazine(943320-61-4)
• EPA Substance Registry System: 3-Ethynylimidazo[1,2-b]pyridazine(943320-61-4)

Safety Data

• Hazardous Substances Data: 943320-61-4(Hazardous Substances Data)

Usage

General Description

3-Ethynylimidazo[1,2-b]pyridazine is a chemical compound with the molecular formula C8H5N3. It belongs to the class of imidazo[1,2-b]pyridazine compounds, which are heterocyclic organic compounds containing a pyridazine ring fused to an imidazole ring. This chemical is known for its potential biological activities, such as anticancer and antiviral properties. It has been studied for its ability to inhibit the growth of cancer cells and to act as an anti-inflammatory agent. Additionally, 3-Ethynylimidazo[1,2-b]pyridazine has shown promise as a potential drug candidate in the development of new medicines. Further research is ongoing to explore its therapeutic applications and potential uses in pharmaceuticals.

Upstream product

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Relevant articles and documents

N-(3-(IMIDAZO[1,2-B]PYRIDAZIN-3-YLETHYNYL)-4-METHYLPHENYL)-5-PHENYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR TREATING KINASE-RELATED DISEASES

The N-(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylphenyl)-5-phenyl-4,5-dihydro-1H-pyrazole-1-carboxamide derivative exhibits excellent inhibitory activity against at least one kinase selected from the group consisting of ABL1, ABL2, AURKB, BRK, CDK11

COMPOUNDS USEFUL FOR INHIBITING RAF DIMERS

The disclosure provides compounds of Formula I (Formula I) (c) And the pharmaceutically acceptable salts thereof. The A, B, C, and D rings and the variables, RA, RB, RC, RD, L0, L1, L2

BTK Inhibitors and uses thereof

The invention discloses a bruton's tyrosine kinase (BTK) inhibitor and use thereof. Specifically, the invention provides heteroaromatic compounds or stereoisomers, geometrical isomers, tautomers, racemates, nitrogen oxides, hydrates, solvates, metabolites and pharmaceutically acceptable salts or prodrugs thereof, and pharmaceutical compositions containing the heteroaromatic compounds; the invention also discloses use of the heteroaromatic compounds or the pharmaceutical compositions containing the heteroaromatic compounds in preparation of medicines; the medicines can be used for treating autoimmune diseases, inflammatory diseases or proliferative diseases.