943320-62-5

Basic information

• Product Name: dimethyl-[(R)-1-(4-nitro-2-trifluoromethyl-benzyl)-pyrrolidin-3-yl]-amine
• Synonyms: dimethyl-[(R)-1-(4-nitro-2-trifluoromethyl-benzyl)-pyrrolidin-3-yl]-amine
• CAS NO: 943320-62-5
• Molecular Weight: 317.311
• Mol File: 943320-62-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: dimethyl-[(R)-1-(4-nitro-2-trifluoromethyl-benzyl)-pyrrolidin-3-yl]-amine(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl-[(R)-1-(4-nitro-2-trifluoromethyl-benzyl)-pyrrolidin-3-yl]-amine(943320-62-5)
• EPA Substance Registry System: dimethyl-[(R)-1-(4-nitro-2-trifluoromethyl-benzyl)-pyrrolidin-3-yl]-amine(943320-62-5)

Safety Data

• Hazardous Substances Data: 943320-62-5(Hazardous Substances Data)

Upstream product

• 89976-12-5 1-methyl-4-nitro-2-(trifluoromethyl) benzene 
• 694499-22-4 1-(bromomethyl)-4-nitro-2-(trifluoromethyl) benzene 

Downstream Products

• 943320-63-6 [(R)-1-(4-amino-2-trifluoromethyl-benzyl)-pyrrolidin-3-yl]-dimethyl-amine 

Relevant articles and documents

SUBSTITUTED PYRIMIDINYL AND PYRIDINYL-PYRROLOPYRIDINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS

The present invention relates to substituted pyrimidinyl- and pyridinylpyrrolopyridinone compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular RET family kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions containing these compounds.

BICYCLIC HETEROARYL COMPOUNDS

This invention relates to compounds of the general formula (I) in which the variable groups are as defined herein, and to their preparation and use.