943771-01-5

Basic information

• Product Name: 3-Pyridinecarbonitrile, 2-amino-6-(1-methylethyl)-
• Synonyms: 3-Pyridinecarbonitrile, 2-amino-6-(1-methylethyl)-;2-amino-6-isopropylnicotinonitrile
• CAS NO: 943771-01-5
• Molecular Formula: C9H11N3
• Molecular Weight: 161.2
• Mol File: 943771-01-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Pyridinecarbonitrile, 2-amino-6-(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarbonitrile, 2-amino-6-(1-methylethyl)-(943771-01-5)
• EPA Substance Registry System: 3-Pyridinecarbonitrile, 2-amino-6-(1-methylethyl)-(943771-01-5)

Safety Data

• Hazardous Substances Data: 943771-01-5(Hazardous Substances Data)

Upstream product

• 943771-00-4 2-bromo-6-isopropyl-nicotinonitrile 
• 563-80-4 3-methyl-butan-2-one 
• 5782-69-4 6-isopropyl-2-oxo-1,2-dihydropyridine-3-carbonitrile 
• 55793-14-1 4-methyl-3-oxo-pentanal; sodium enolate 

Downstream Products

• 1365921-39-6 C₂₃H₂₂N₄S 
• 944503-88-2 C₂₅H₂₅N₅OS 
• 944503-77-9 C₂₃H₂₂N₄OS 
• 944503-94-0 C₂₄H₂₄N₄OS 
• 1365921-60-3 C₂₃H₂₁FN₄S 
• 943771-13-9 4-(4-amino-phenylsulfanyl)-N-(4-bromo-phenyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-benzamide 
• 943774-52-5 4-(4-amino-phenylsulfanyl)-N-(4-fluoro-phenyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-N-methyl-benzamide 
• 943773-01-1 N-(4-bromo-phenyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-4-[4-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenylsulfanyl]-benzamide 
• 943774-56-9 {4-[4-[(4-fluoro-phenyl)-methyl-carbamoyl]-2-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenylsulfanyl]-phenyl}-carbamic acid 2,2,2-trichloro-ethyl ester 
• 943772-98-3 {4-[4-(4-bromo-phenylcarbamoyl)-2-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenylsulfanyl]-phenyl}-carbamic acid 2,2,2-trichloro-ethyl ester 
• 943776-57-6 furan-2-carboxylic acid [4-(4-hydroxy-phenylsulfanyl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-phenyl]-amide 

Relevant articles and documents

Novel Hepatitis C virus replicon inhibitors: Synthesis and structure-activity relationships of fused pyrimidine derivatives

The synthesis of several pyrido[2,3-d]pyrimidine and pyrimido[4,5-d] pyrimidine analogs is described with one such analog possessing subnanomolar potency in both genotype 1a and 1b cell culture HCV replicon assays.

ANTI-VIRAL COMPOUNDS

Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.