943845-23-6 Usage
Description
[1,2,4]TRIAZOLO[1,5-A]PYRIDINE-6-CARBONITRILE, with the molecular formula C7H4N6, is a chemical compound belonging to the class of triazolopyridine derivatives. It is characterized by a pyridine ring fused to a triazole ring, making it a versatile building block in organic synthesis and a promising intermediate in the development of pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
[1,2,4]TRIAZOLO[1,5-A]PYRIDINE-6-CARBONITRILE is used as an intermediate for the synthesis of various biologically active compounds, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
[1,2,4]TRIAZOLO[1,5-A]PYRIDINE-6-CARBONITRILE is also used as an intermediate in the synthesis of agrochemicals, playing a role in the development of compounds for agricultural applications, such as pesticides and herbicides.
Used in Medicinal Chemistry and Drug Discovery:
Due to its unique structure and pharmacological properties, [1,2,4]TRIAZOLO[1,5-A]PYRIDINE-6-CARBONITRILE has potential applications in the field of medicinal chemistry and drug discovery, where it can be utilized to create novel compounds with specific biological activities.
Safety Note:
It is important to handle [1,2,4]TRIAZOLO[1,5-A]PYRIDINE-6-CARBONITRILE with caution and follow proper safety protocols when working with it in a laboratory setting to ensure the safety of researchers and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 943845-23-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,3,8,4 and 5 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 943845-23:
(8*9)+(7*4)+(6*3)+(5*8)+(4*4)+(3*5)+(2*2)+(1*3)=196
196 % 10 = 6
So 943845-23-6 is a valid CAS Registry Number.
943845-23-6Relevant articles and documents
Discovery of (S)-1-(1-(Imidazo[1,2- a ]pyridin-6-yl)ethyl)-6-(1-methyl-1 H -pyrazol-4-yl)-1 H -[1,2,3]triazolo[4,5- b ]pyrazine (Volitinib) as a Highly Potent and Selective Mesenchymal-Epithelial Transition Factor (c-Met) Inhibitor in Clinical Development for Treatment of Cancer
Jia, Hong,Dai, Guangxiu,Weng, Jianyang,Zhang, Zhulin,Wang, Qing,Zhou, Feng,Jiao, Longxian,Cui, Yumin,Ren, Yongxin,Fan, Shiming,Zhou, Jinghong,Qing, Weiguo,Gu, Yi,Wang, Jian,Sai, Yang,Su, Weiguo
, p. 7577 - 7589 (2014/12/11)
HGF/c-Met signaling has been implicated in human cancers. Herein we describe the invention of a series of novel triazolopyrazine c-Met inhibitors. The structure-activity relationship of these compounds was investigated, leading to the identification of compound 28, which demonstrated favorable pharmacokinetic properties in mice and good antitumor activities in the human glioma xenograft model in athymic nude mice.
HETERO COMPOUND
-
Page/Page column 30, (2009/01/24)
[Problems] To provide a useful compound as an active ingredient for a preventing and/or treating agent for rejection in the transplantation of an organ, bone marrow, or a tissue, an autoimmune disease, or the like, which has an excellent S1P1 a
