94385-81-6

Basic information

• Product Name: (3RS,4SR)-3,4-dihydroxy-3-(3,4-dimethoxybenzyl)-7-methoxychroman
• CAS NO: 94385-81-6
• Molecular Weight: 346.38
• Mol File: 94385-81-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3RS,4SR)-3,4-dihydroxy-3-(3,4-dimethoxybenzyl)-7-methoxychroman(CAS DataBase Reference)
• NIST Chemistry Reference: (3RS,4SR)-3,4-dihydroxy-3-(3,4-dimethoxybenzyl)-7-methoxychroman(94385-81-6)
• EPA Substance Registry System: (3RS,4SR)-3,4-dihydroxy-3-(3,4-dimethoxybenzyl)-7-methoxychroman(94385-81-6)

Safety Data

• Hazardous Substances Data: 94385-81-6(Hazardous Substances Data)

Upstream product

• 18385-89-2 3-chromene 
• 57543-39-2 7-methoxy-2H-chromene-3-carbaldehyde 
• 91100-82-2 7-Benzyloxy-3-[1-(4-benzyloxy-3-methoxy-phenyl)-meth-(E)-ylidene]-chroman-4-one 
• 121-33-5 vanillin 
• 111254-31-0 (E)-3-(4-hydroxy-3-methoxybenzylidene)-7-hydroxychroman-4-one 
• 76240-27-2 7-hydroxy-2,3-dihydro-4H-chromen-4-one 
• 111254-21-8 (3RS,4SR)-3-(4-hydroxy-3-methoxybenzyl)-3,4,7-trihydroxychroman <(+/-)-3'-O-methylsappanol> 
• 77-78-1 dimethyl sulfate 
• 102067-87-8 (3RS,4SR)-3-(3,4-dihydroxybenzyl)-3,4,7-trihydroxychroman <(+/-)-sappanol> 
• 111254-21-8 (3RS,4RS)-3-(4-hydroxy-3-methoxybenzyl)-3,4,7-trihydroxychroman <(+/-)-3'-O-methylepisappanol> 
• 111254-34-3 (3R,4S)-7-Benzyloxy-3-(4-benzyloxy-3-methoxy-benzyl)-chroman-3,4-diol 
• 111276-58-5 C₃₁H₂₆O₆ 
• 111254-34-3 (3R,4R)-7-Benzyloxy-3-(4-benzyloxy-3-methoxy-benzyl)-chroman-3,4-diol 

Relevant articles and documents

A concise synthetic approach to brazilin via Pd-catalyzed allylic arylation

A short synthetic route to the trimethyl ether of brazilin was developed in 6 steps from 7-methoxychromene with 78% overall yield. Regioselective installation of a formyl group onto 7-methoxychromene followed by reduction and acetylation afforded allylic acetate. Palladium-catalyzed allylic coupling of allylic acetate with arylboronic acid provided direct access to 3-benzylchromene which was converted to the target molecule upon ensuing dihydroxylation and acid-catalyzed cyclization in a highly concise manner. This journal is