943960-92-7Relevant articles and documents
In vitro efficacy of 7-benzylamino-1-isoquinolinamines against Plasmodium falciparum related to the efficacy of chalcones
Gutteridge, Clare E.,Hoffman, Marshall M.,Bhattacharjee, Apurba K.,Milhous, Wilbur K.,Gerena, Lucia
, p. 786 - 789 (2011/03/17)
A series of 1,7-diaminoisoquinolinamines, that are expected to mediate antimalarial activity by the same mechanism employed by the chalcones, were produced. Six 7-benzylamino-1-isoquinolinamines were found to be submicromolar inhibitors in vitro of drug-r