94426-71-8

Basic information

• Product Name: (+/-)-4-(2-benzyloxyethyl)-2,2-dimethyl-1,3-dioxolane
• Synonyms: (+/-)-4-(2-benzyloxyethyl)-2,2-dimethyl-1,3-dioxolane
• CAS NO: 94426-71-8
• Molecular Weight: 236.311
• Mol File: 94426-71-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (+/-)-4-(2-benzyloxyethyl)-2,2-dimethyl-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-4-(2-benzyloxyethyl)-2,2-dimethyl-1,3-dioxolane(94426-71-8)
• EPA Substance Registry System: (+/-)-4-(2-benzyloxyethyl)-2,2-dimethyl-1,3-dioxolane(94426-71-8)

Safety Data

• Hazardous Substances Data: 94426-71-8(Hazardous Substances Data)

Upstream product

• 5754-34-7 4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 
• 3068-00-6 D,L-1,2,4-butanetriol 

Downstream Products

• 71998-69-1 (+/-)-4-benzyloxy-butane-1,2-diol 
• 1312706-50-5 (+/-)-[3-(t-butyldimethylsilanyloxy)-3-(t-butyldimethylsilanyloxymethyl)pent-4-enyloxymethyl]benzene 
• 1312706-49-2 (+/-)-5-benzyloxy-3-(t-butyldimethylsilanyloxymethyl)pent-1-en-3-ol 
• 1312706-48-1 4-benzyloxy-1-(t-butyldimethylsilanyloxy)-butan-2-one 
• 19790-60-4 3-Benzyloxypropanal 
• 186090-93-7 2-azi-4-benzyloxy-1-(2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyloxy)butane 
• 186090-90-4 (+/-)-4-benzyloxy-1-triphenylmethyloxy-2-butanol 
• 186090-91-5 4-benzyloxy-1-triphenylmethyloxy-2-butanone 
• 186090-92-6 [3-(2-Benzyloxy-ethyl)-3H-diazirin-3-yl]-methanol 
• 185155-48-0 4-benzyloxy-1-hydroxybutan-2-one 
• 171110-94-4 4-<(2-benzyloxy)ethyl>-1,3-dioxolan-2-one 
• 94426-77-4 9-<4-(benzyloxy)-2-oxobutyl>guanine 
• 94426-73-0 9-<4-(benzyloxy)-2-hydroxybutyl>guanine 
• 94426-78-5 9-<4-(benzyloxy)-2-oxobutyl>adenine 

Relevant articles and documents

Condensation of 1,2,4-Butanetriol with Carbonyl Compounds and Reactions of Hydroxyalkyl-1,3-dioxacyclanes

A mixture of isomers of 2-(1,3-dioxolan-4-yl)ethanol and 1,3-dioxan-4-ylmethanol was prepared by reaction of 1,2,4-butanetriol with paraformaldehyde. This mixture was subjected to O-alkylation, O-acylation, condensation with phenyl isocyanate, and substitution of OH groups for Cl. The relative activity of acetone derivatives of glycerol and 1,2,4-butanetriol in reactions with allyl chloride and benzyl chloride was estimated.

Synthesis of diether-linked cationic lipids for gene delivery

Quaternary ammonium lipids 1b-d, with diether linkages between hydrocarbon chains and butane or hexane backbone, were synthesized for cationic liposome-mediated gene delivery. The synthetic strategy of using C- 4 or C-6 synthon permits the achievement of the variation of the hydrophobic domain as well as changes of space between the quaternary ammonium head and the hydrophobic domain in the diether-linked cationic lipids.

Synthesis of 9-(4-hydroxy-2-oxobutyl)guanine, 9-(2,4-dihydroxybutyl)guanine, and related acyclic nucleoside analogues

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