944283-07-2 Usage
Description
Boc-Ser(Fmoc-Ala)-OH is a complex chemical compound consisting of a Boc-protected serine residue bonded to a Fmoc-protected alanine residue through a peptide bond. The Boc group acts as a protecting group for the serine residue, while the Fmoc group serves a similar purpose for the alanine residue. Boc-Ser(Fmoc-Ala)-OH is a crucial building block in organic chemistry and biochemistry, with significant applications in pharmaceutical research, drug development, and biotechnology.
Uses
Used in Pharmaceutical Research:
Boc-Ser(Fmoc-Ala)-OH is used as a key component in the synthesis of peptides and proteins for pharmaceutical research. The protecting groups allow for selective removal, enabling further modifications and reactions to create novel therapeutic agents.
Used in Drug Development:
In drug development, Boc-Ser(Fmoc-Ala)-OH serves as an essential building block for the creation of new drugs. Its ability to be selectively modified makes it a versatile tool in the development of innovative pharmaceuticals.
Used in Biotechnology:
Boc-Ser(Fmoc-Ala)-OH is utilized in biotechnology for the synthesis of bioactive peptides and proteins. Its role in creating complex peptide structures contributes to advancements in areas such as diagnostics, therapeutics, and bioengineering.
Check Digit Verification of cas no
The CAS Registry Mumber 944283-07-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,2,8 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 944283-07:
(8*9)+(7*4)+(6*4)+(5*2)+(4*8)+(3*3)+(2*0)+(1*7)=182
182 % 10 = 2
So 944283-07-2 is a valid CAS Registry Number.
944283-07-2Relevant articles and documents
Synthesis of cyclic peptides via O-N-acyl migration
Lécaillon, Jennifer,Gilles, Pierre,Subra, Gilles,Martinez, Jean,Amblard, Muriel
, p. 4674 - 4676 (2008/12/20)
We describe here a novel and convenient synthesis of head-to-tail cyclic peptide avoiding racemization. Linear depsipeptides including a serine residue as the key element for ester bond formation and acyl transfer were synthesized on 2-chlorotrityl chloride resin. After cleavage from the resin, intramolecular head-to-tail cyclization was performed in solution by C-terminal activation of urethane protected O-acyl serine residue. After removal of the Nα-serine protecting group, the final step consisted in O-N-acyl migration reaction on the 'switch' or 'click' element to restore native cyclic peptides.