944317-92-4

Basic information

• Product Name: 1-BroMo-4-fluoro-5-isopropyl-2-Methoxybenzene
• Synonyms: 1-BroMo-4-fluoro-5-isopropyl-2-Methoxybenzene;1-BroMo-4-fluoro-5-isopro...;Benzene, 1-broMo-4-fluoro-2-Methoxy-5-(1-Methylethyl)-;1-bromo-4-fluoro-2-methoxy-5-(propan-2-yl)benzene;EOS-61123
• CAS NO: 944317-92-4
• Molecular Formula: C₁₀H₁₂BrFO
• Molecular Weight: 247.1040832
• Mol File: 944317-92-4.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 240.1±40.0℃ (760 Torr)
• Flash Point: 124.3±11.6℃
• Appearance: /
• Density: 1.343±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-BroMo-4-fluoro-5-isopropyl-2-Methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BroMo-4-fluoro-5-isopropyl-2-Methoxybenzene(944317-92-4)
• EPA Substance Registry System: 1-BroMo-4-fluoro-5-isopropyl-2-Methoxybenzene(944317-92-4)

Safety Data

• Hazardous Substances Data: 944317-92-4(Hazardous Substances Data)

Usage

General Description

1-Bromo-4-fluoro-5-isopropyl-2-methoxybenzene is a chemical compound with the molecular formula C10H12BrFO. It is a derivative of benzene and contains a bromine, fluorine, isopropyl, and methoxy group attached to the benzene ring. 1-Bromo-4-fluoro-5-isopropyl-2-methoxybenzene is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also employed as a building block in the production of various organic compounds. Additionally, 1-Bromo-4-fluoro-5-isopropyl-2-methoxybenzene has potential applications in the field of organic synthesis and materials science. It is important to handle this chemical with care as it may pose health and environmental risks if not properly managed.

Upstream product

• 1262414-96-9 2-(2-fluoro-4-methoxyphenyl)isopropane 
• 914221-54-8 1-(5-bromo-2-fluoro-4-methoxyphenyl)ethan-1-one 
• 958029-46-4 2-(5-bromo-2-fluoro-4-methoxyphenyl)propan-2-ol 
• 348-57-2 2,4-difluorobromobenzene 
• 450-88-4 1-bromo-4-fluoro-2-methoxybenzene 
• 74457-86-6 1-(2-fluoro-4-methoxyphenyl)-1-ethanone 
• 96826-25-4 2-(2-fluoro-4-methoxyphenyl)-2-isopropanol 
• 1383814-82-1 1-bromo-4-fluoro-2-methoxy-5-(1-methylvinyl)benzene 
• 875446-55-2 2-fluoro-4-methoxy-1-(prop-1-en-2-yl)benzene 
• 446-35-5 2,4-Difluoronitrobenzene 
• 446-36-6 5-fluoro-2-nitrophenol 
• 448-19-1 4-fluoro-2-methoxy-1-nitrobenzene 
• 450-91-9 4-fluoro-2-methoxyaniline 

Downstream Products

• 875446-29-0 [4-fluoro-2-methoxy-5-(propan-2-yl)phenyl]boronic acid 
• 875548-97-3 (4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)methanol 
• 875548-98-4 2'-(bromomethyl)-4-fluoro-2-methoxy-5-(propan-2-yl)-4'-(trifluoromethyl)biphenyl 
• 1370452-28-0 5-(3,5-bis(trifluoromethyl)phenyl)-3-((4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl)methyl)-4-methylthiazolidin-2-one 
• 875446-37-0 anacetrapib 
• 875551-28-3 2'-(chloromethyl)-4-fluoro-5-isopropyl-2-methoxy-4'-(trifluoromethyl)biphenyl 

Relevant articles and documents

Novel synthetic method for (4-fluoro-5-isopropyl-methoxyphenyl)boric acid

The invention discloses a novel synthetic method for (4-fluoro-5-isopropyl-methoxyphenyl)boric acid. According to the method, easily available and cheap 2-fluoro-4-methoxyacetophenone is used as a raw material and subjected to a Witting reaction, a hydrog

Process for a CETP Inhibitor

An efficient process is disclosed for producing the compound of formula I, which is the CETP inhibitor anacetrapib, which raises HDL-cholesterol and reduces LDL-cholesterol in human patients and may be effective for treating or reducing the risk of developing atherosclerosis:

SYNTHESIS OF INTERMEDIATES FOR PREPARING ANACETRAPIB AND DERIVATIVES THEREOF

The present invention relates to the field of organic chemistry, more specifically to the synthesis of intermediate compounds which can be used in the synthesis of pharmaceutically active agents such as anacetrapib or derivatives thereof.