94475-59-9

Basic information

• Product Name: 2-Propenamide, N-[2-(1H-indol-3-yl)ethyl]-3-[3-methoxy-4-(phenylmethoxy)phenyl]-, (E)-
• CAS NO: 94475-59-9
• Molecular Formula: C27H26N2O3
• Molecular Weight: 426.515
• Mol File: 94475-59-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Propenamide, N-[2-(1H-indol-3-yl)ethyl]-3-[3-methoxy-4-(phenylmethoxy)phenyl]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenamide, N-[2-(1H-indol-3-yl)ethyl]-3-[3-methoxy-4-(phenylmethoxy)phenyl]-, (E)-(94475-59-9)
• EPA Substance Registry System: 2-Propenamide, N-[2-(1H-indol-3-yl)ethyl]-3-[3-methoxy-4-(phenylmethoxy)phenyl]-, (E)-(94475-59-9)

Safety Data

• Hazardous Substances Data: 94475-59-9(Hazardous Substances Data)

Upstream product

• 343-94-2 tryptamine hydochloride 
• 94475-60-2 3-(O-benzylferulyl)-1,3-thiazolidine-2-thione 
• 74058-78-9 N-(p-hydroxyethylphenyl)hexadecanamide 
• 134469-06-0 thiazolidine-2-thione 
• 111-49-9 hexamethylene imine 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 34159-46-1 dimethylphosphonoacetic acid 

Downstream Products

• 96014-22-1 (E)-N-(2-(1H-indol-3-yl)ethyl)-3-(4-hydroxy-3-methoxyphenyl)acrylamide 

Relevant articles and documents

A CONVENIENT METHOD FOR THE SYNTHESIS OF αβ-UNSATURATED CARBOXYLIC ACID AMIDES UTILIZING A NEW HETERO-BIFUNCTIONAL REAGENT, DMPATT

As a new extention of monitored aminolysis of 3-acyl-1,3-thiazolidine-2-thione(ATT), a convenient procedure for the synthesis of αβ-unsaturated carboxylic acid amides has been developed using a new hetero-bifunctional reagent, 3-dimethylphosphonoacetyl-1,3-thiazolidine-2-thione (DMPATT).DMPATT was effectively used as the bridging reagent between amino (or imino) compounds and aldehydes (or ketone) to afford various olefinic amides in good yields.KEYWORDS - thiazolidine-2-thione; hetero-bifunctional reagent; αβ-unsaturated amide; Wittig reaction; ferulyltryptamine

MONITORED AMINOLYSIS OF 3-ACYLTHIAZOLIDINE-2-THIONE : A NEW CONVENIENT SYNTHESIS OF AMIDE

3-Acylthiazolidine-2-thiones (1) were easily prepared and they were treated with several amines in dichloromethane to give amides 4 in very high yields within a short time.Aminoalcohols and aminophenols were selectively converted into acylaminoalcohols and acylaminophenols, respectively, by this reaction.One can monitor the reaction by disappearance of the yellow color of the starting material 1.Some amide alkaloids (15-18) have effectively been synthesized.