945028-65-9Relevant articles and documents
Optimization of novel combi-molecules: Identification of balanced and mixed bcr-abl/DNA targeting properties
Rachid, Zakaria,Katsoulas, Athanasia,Williams, Christopher,Larroque, Anne-Laure,McNamee, James,Jean-Claude, Bertrand J.
, p. 4248 - 4253 (2008/02/09)
Steps toward the identification of combi-molecules with strong abl tyrosine kinase (TK) inhibitory property and significant DNA damaging potential are described. The optimized combi-molecule 13a was shown to induce approximately twofold stronger abl TK in