945606-99-5 Usage
Description
(S)-BoroLeu-(-)-Pinanediol-hydrochloride, also known as (αS,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-α-(2-methylpropyl)-4,6-Methano-1,3,2-benzodioxaborole-2-methanamine Hydrochloride, is a chiral reagent with a unique molecular structure. It is characterized by its chiral centers and the presence of a benzodioxaborole ring, which contributes to its specific properties and applications.
Uses
Used in Pharmaceutical Industry:
(S)-BoroLeu-(-)-Pinanediol-hydrochloride is used as a chiral reagent for the preparation of isocoumarin analogs. These analogs serve as inhibitors of γ-secretase cleavage of APP (Amyloid Precursor Protein), which is a crucial target for the development of drugs aimed at treating Alzheimer's disease. The chiral nature of this reagent ensures the selective synthesis of desired enantiomers, which is essential for the biological activity and safety of the final drug product.
Used as Bortezomib Impurity 37:
In the context of pharmaceutical manufacturing, (S)-BoroLeu-(-)-Pinanediol-hydrochloride is also utilized as Bortezomib Impurity 37. Bortezomib is a proteasome inhibitor used for the treatment of multiple myeloma and mantle cell lymphoma. The identification and control of impurities, such as Bortezomib Impurity 37, are vital for ensuring the quality, safety, and efficacy of the drug. This reagent aids in the analytical processes and quality control measures during the production of Bortezomib.
Check Digit Verification of cas no
The CAS Registry Mumber 945606-99-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,5,6,0 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 945606-99:
(8*9)+(7*4)+(6*5)+(5*6)+(4*0)+(3*6)+(2*9)+(1*9)=205
205 % 10 = 5
So 945606-99-5 is a valid CAS Registry Number.
