945668-94-0 Usage
Description
Quetiapine Dimer Impurity, also known as Quetiapine EP Impurity D, is an impurity found in Quetiapine, a medication used to treat various mental health conditions. It is characterized by its pale yellow solid appearance.
Uses
Used in Pharmaceutical Industry:
Quetiapine Dimer Impurity is used as a reference material for quality control and analytical testing in the pharmaceutical industry. It helps ensure the purity and safety of Quetiapine medications by providing a known impurity for comparison and detection during the manufacturing process. This contributes to maintaining the overall quality and efficacy of Quetiapine-based treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 945668-94-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,5,6,6 and 8 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 945668-94:
(8*9)+(7*4)+(6*5)+(5*6)+(4*6)+(3*8)+(2*9)+(1*4)=230
230 % 10 = 0
So 945668-94-0 is a valid CAS Registry Number.
945668-94-0Relevant articles and documents
SYNTHESIS OF 11-(4[-(2-HYDROXYETHOXY)ETHYL]-PIPERAZINYL)-DIBENZO[b,f][1,4]THIAZEPINE AND ITS FUMARATE SALT
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Page/Page column 11, (2008/06/13)
The invention is directed a method for synthesizing l l-(4-[2-(2- hydroxyethoxy)ethyl]-piperazinyl)-dibenzo[b,f] [l,4]thiazepine (quetiapine) and for recovering quetiapine as its fumarate salt in which dibenzo[b,f][l,4]thiazepine- l l(10H)one is chlorinated in the presence of a trialkyl amine base using a slight molar excess of phosphorous oxychloride to produce l l-chloro-dibenzo[b,f] [l,4]thiazepine which then is alkylated with piperazine to l l-piperazinyldibenzo[b,f] [l,4]thiazepine, which finally is alkylated with 2-(2-chloroethoxy)ethanol.
