94590-64-4

Basic information

• Product Name: Benzenebutanoic acid, a-[(2,3,4,5-tetrahydro-4-oxo-1,5-benzothiazepin-3-yl)imino]-, ethyl ester, (R)-
• CAS NO: 94590-64-4
• Molecular Formula: C21H22N2O3S
• Molecular Weight: 382.483
• Mol File: 94590-64-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenebutanoic acid, a-[(2,3,4,5-tetrahydro-4-oxo-1,5-benzothiazepin-3-yl)imino]-, ethyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenebutanoic acid, a-[(2,3,4,5-tetrahydro-4-oxo-1,5-benzothiazepin-3-yl)imino]-, ethyl ester, (R)-(94590-64-4)
• EPA Substance Registry System: Benzenebutanoic acid, a-[(2,3,4,5-tetrahydro-4-oxo-1,5-benzothiazepin-3-yl)imino]-, ethyl ester, (R)-(94590-64-4)

Safety Data

• Hazardous Substances Data: 94590-64-4(Hazardous Substances Data)

Upstream product

• 1493-27-2 ortho-nitrofluorobenzene 
• 94590-53-1 S-(o-nitrophenyl)-N-(carbobenzyloxy)-L-cysteine 
• 94590-54-2 S-(o-aminophenyl)-N-(carbobenzyloxy)-L-cysteine 
• 94590-55-3 3(R)-<(carbobenzyloxy)amino>-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 
• 91088-54-9 N-acetyl-S-(2-nitro-phenyl)-L-cysteine 
• 60115-45-9 S-(o-nitrophenyl)-L-cysteine 
• 64920-29-2 2-oxo-4-phenylbutanoic acid ethyl ester 
• 94590-63-3 (3R)-3-Amino-2,3-dihydro-1,5-benzothiazepin-4(5H)-on 

Downstream Products

• 94590-58-6 (R)-3-<(S)-1-carboxy-3-phenylpropyl>amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-5-acetic acid 
• 94590-62-2 3(R)-amino>-5-(carboxymethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one hydrochloride 
• 94590-60-0 3(R)-amino>-5-(carboxymethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one hydrochloride 
• 94590-34-8 3(R)-[N-(1(S)-carboxy-3-phenylpropyl)amino]-5-(carboxymethyl)-2,3-dihydro-1-oxo-1,5-benzothiazepin-4(5H)-one 
• 94590-33-7 (S)-2-((R)-5-Methoxycarbonylmethyl-1,4-dioxo-2,3,4,5-tetrahydro-1H-1λ⁴-benzo[b][1,4]thiazepin-3-ylamino)-4-phenyl-butyric acid ethyl ester 
• 94590-57-5 3(R)-[N-(1(R)-carboxy-3-phenylpropyl)amino]-5-(carboxymethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 
• 94590-51-9 3(R)-amino>-5-(carbomethoxymethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 
• 94590-52-0 3(R)-amino>-5-(carbomethoxymethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 
• 97277-72-0 3(R)-amino>-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 
• 94590-61-1 3(R)-amino>-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 

Relevant articles and documents

Angiotensin converting enzyme inhibitors: 1,5-Benzothiazepine derivatives

The synthesis of chiral 1,5-benzothiazepines 2a-c, 14a-c, 15c, and 16a prepared from cysteine is described. In vitro inhibition of angiotensin converting enzyme (ACE) is reported for each compound. Compound 2c was the most potent in vitro having an ICsub