945986-15-2

Basic information

• Product Name: C₂₁H₂₃NO₅
• Synonyms: C₂₁H₂₃NO₅
• CAS NO: 945986-15-2
• Molecular Weight: 369.417
• Mol File: 945986-15-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₃NO₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₃NO₅(945986-15-2)
• EPA Substance Registry System: C₂₁H₂₃NO₅(945986-15-2)

Safety Data

• Hazardous Substances Data: 945986-15-2(Hazardous Substances Data)

Upstream product

• 96-86-6 diethyl benzamidomalonate 
• 100-44-7 benzyl chloride 

Downstream Products

• 945986-05-0 2-benzoylamino-2-benzylmalonic acid monoethyl ester 
• 64896-35-1 (R)-2-(N-benzoylamino)-3-phenylpropanoic acid ethyl ester 
• 19817-70-0 (S)-ethyl N-benzoyl-phenylalaninate 

Relevant articles and documents

Highly enantioselective decarboxylative protonation of α- aminomalonates mediated by thiourea Cinchona alkaloid derivatives: Access to both enantiomers of cyclic and acyclic α-aminoacids

Equation Presented Thiourea derived cinchona alkaloids promote the asymmetric decarboxylase protonation of cyclic, acyclic, or bicyclic α-aminomalonate hemiesters under mild and metal-free conditions to afford enantioenriched aminoesters in high yields and enantioselectivities up to 93%. Both enantiomers of the aminoesters have been synthesized with the same selectivity when using organic base 3 and its pseudoenantiomer 6 derived from quinine.