946-65-6 Usage
Description
3-(TRIFLUOROMETHYLTHIO)BENZOIC ACID is a chemical compound characterized by the presence of a trifluoromethylthio group. This group endows the compound with unique properties that make it valuable for the development of new dyes, medicinal agents, and novel heterocyclic systems.
Uses
Used in Pharmaceutical Industry:
3-(TRIFLUOROMETHYLTHIO)BENZOIC ACID is used as a key intermediate in the synthesis of medicinal agents for various therapeutic applications. Its trifluoromethylthio group contributes to the compound's chemical reactivity and stability, making it suitable for the development of new drugs with improved pharmacological properties.
Used in Dye Industry:
3-(TRIFLUOROMETHYLTHIO)BENZOIC ACID is used as a precursor in the preparation of new dyes with enhanced color properties and stability. The trifluoromethylthio group imparts unique characteristics to the dyes, allowing for the creation of innovative colorants with improved performance in various applications.
Used in Chemical Research:
3-(TRIFLUOROMETHYLTHIO)BENZOIC ACID is utilized in the synthesis of novel heterocyclic systems for chemical research. The trifluoromethylthio group provides a versatile platform for the exploration of new chemical structures and their potential applications in various fields, including materials science and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 946-65-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,4 and 6 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 946-65:
(5*9)+(4*4)+(3*6)+(2*6)+(1*5)=96
96 % 10 = 6
So 946-65-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H5F3O2S/c9-8(10,11)14-6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)/p-1
946-65-6Relevant articles and documents
Electrochemical Trifluoromethylation of Thiophenols with Sodium Trifluoromethanesulfinate
Zhu, Xing-Xing,Wang, Huai-Qin,Li, Chen-Guang,Xu, Xiao-Lan,Xu, Jun,Dai, Jian-Jun,Xu, Hua-Jian
, p. 16114 - 16120 (2021/02/03)
We developed an electrochemical trifluoromethylation of thiophenols without the use of metal catalysts and oxidants. This reaction features mild reaction conditions, readily available substrate, as well as moderate to good yields. In addition, this protocol can be easily scaled up with moderate efficiency.
Sandmeyer trifluoromethylthiolation of arenediazonium salts with sodium thiocyanate and Ruppert-Prakash reagent
Danoun, Gregory,Bayarmagnai, Bilguun,Gruenberg, Matthias F.,Goossen, Lukas J.
, p. 1312 - 1316 (2014/03/21)
In the presence of copper thiocyanate, sodium thiocyanate and the inexpensive, easy-to-use trifluoromethylating reagent Me3Si-CF 3, diazonium salts are smoothly converted into the corresponding aryl trifluoromethyl thioethers. Combin
ACID-BASE PROPERTIES OF (PERFLUOROALKYLTHIO)- AND (PERFLUOROALKYLSULFONYL)-SUBSTITUTED BENZOIC ACIDS AND ANILINES
Kondratenko, N. V.,Kolomeitsev, A. A.,Popov, V. I.,Il'chenko, A. Ya.,Korzhenevskaya, N. G.,et al.
, p. 2254 - 2258 (2007/10/02)
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