946402-82-0

Basic information

• Product Name: 2-(2-chlorophenyl)-N-methoxy-N-methylacetamide
• Synonyms: 2-(2-chlorophenyl)-N-methoxy-N-methylacetamide
• CAS NO: 946402-82-0
• Molecular Weight: 213.664
• Mol File: 946402-82-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(2-chlorophenyl)-N-methoxy-N-methylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-chlorophenyl)-N-methoxy-N-methylacetamide(946402-82-0)
• EPA Substance Registry System: 2-(2-chlorophenyl)-N-methoxy-N-methylacetamide(946402-82-0)

Safety Data

• Hazardous Substances Data: 946402-82-0(Hazardous Substances Data)

Usage

Amide derivative

It is a compound derived from a carboxylic acid by replacing the hydroxyl group (-OH) with an amide group (-NR2).

Methoxy group

-OCH3 A methoxy group is an ether functional group consisting of an oxygen atom bonded to a methyl group (-CH3), which is attached to the nitrogen atom in this compound.

Chlorophenyl group

-C6H4Cl A chlorophenyl group is a phenyl ring (a six-membered carbon ring with alternating single and double bonds) with a chlorine atom attached to it, which is attached to the carbon atom in this compound.

Intermediate in synthesis

2-(2-chlorophenyl)-N-methoxy-N-methylacetamide is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, meaning it is a reactant in the production of these compounds.

Potential medical applications

The compound has been investigated for its potential use in treating conditions such as chronic pain and epilepsy.

Applications in material development

It may have applications in the development of new materials and chemical processes.

Health and environmental hazards

This compound may pose health and environmental hazards if not handled and disposed of properly, indicating the need for proper safety precautions and disposal methods.

Upstream product

• 2444-36-2 2'-chloro-benzeneacetic acid 
• 51512-09-5 2-(2-chlorophenyl)acetyl chloride 
• 1117-97-1 N,0-dimethylhydroxylamine 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 

Downstream Products

• 57479-60-4 1-phenyl-2-(2-chlorophenyl)ethanone 
• 178928-70-6 2?[(2RS)?2?(1?chlorocyclopropyl)?3?(2?chlorophenyl)?2?hydroxypropyl]?2H?1,2,4?triazole?3(4H)?thione 
• 6305-95-9 2-chlorophenylacetone 

Relevant articles and documents

Synthesis method and application of prothioconazole

The invention relates to the technical field of chemical drug synthesis, and especially relates to a synthesis method and application of prothioconazole. The synthesis method of prothioconazole comprises the following steps: 1, carrying out an epoxidation reaction on a compound represented by formula IV to obtain a compound represented by formula III; 2, performing nucleophilic addition reaction on the compound of the formula III and triazole to obtain a compound represented by formula II; and 3, carrying out a vulcanization reaction on the compound of the formula II to obtain prothioconazolerepresented by formula I. The prothioconazole is prepared by taking the compound of the formula IV as an initial raw material through the epoxidation reaction, the nucleophilic addition reaction and the vulcanization reaction, so the cost is low, safety and high efficiency are achieved, potential safety hazards are avoided, the overall yield is high, reaction conditions are mild, the raw materialutilization rate is increased, three wastes can be obviously reduced, and the method has certain significance for industrial production.

Enantioselective Mannich Reaction Employing 1,3,5-Triaryl-1,3,5-triazinanes Catalyzed by Chiral-at-Metal Rhodium Complexes

Chiral-at-metal RhIII complexes catalyze the efficient enantioselective Mannich reaction of 2-acyl imidazoles with 1,3,5-triazinanes, affording the corresponding adducts in 81–99 % yield with up to >99 % enantioselectivity. This protocol performs with 0.1 mol-% of RhIII complex on gram scale without any loss in enantioselectivity.

N-HYDROXYACRYLAMIDE COMPOUNDS

This invention relates to novel N-hydroxyacrylamide compounds of formula (I) and pharmaceutically acceptable salts thereof . More particularly, it relates to novel N-hydroxyacrylamide compounds and pharmaceutically acceptable salts thereof which act as a