946517-54-0Relevant articles and documents
Antitumor imide derivatives of 7-oxabicyclo[2.2.1]heptane-2,3-dimethyl-2,3-dicarboxylic acid
Walter
, p. 66 - 67 (2007/10/02)
The imide and methylimide derivatives of 7-oxobicyclo-[2.2.1]heptane-2,3-dimethyl-2,3-dicarboxylic acid were synthesized and shown to have antitumor inhibitory activity (growth inhibition) against the KB cell line. The compounds were prepared according to standard procedures. Interest in the respective imide derivatives stemmed from their structural relationship to antitumor-active derivatives of 7-oxobicyclo[2.2.1]heptane-2,3-dicarboxylic acid which lacked 2,3-dimethyl substituents or which were derivatives of isoindolines and lacked the carbonyl groups.