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946822-60-2

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946822-60-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 946822-60-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,6,8,2 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 946822-60:
(8*9)+(7*4)+(6*6)+(5*8)+(4*2)+(3*2)+(2*6)+(1*0)=202
202 % 10 = 2
So 946822-60-2 is a valid CAS Registry Number.

946822-60-2Relevant articles and documents

Identification of novel, potent and selective inhibitors of Polo-like kinase 1

Chen, Shaoqing,Bartkovitz, David,Cai, Jianping,Chen, Yi,Chen, Zhi,Chu, Xin-Jie,Le, Kang,Le, Nam T.,Luk, Kin-Chun,Mischke, Steve,Naderi-Oboodi, Goli,Boylan, John F.,Nevins, Tom,Qing, Weiguo,Chen, Yingsi,Wovkulich, Peter M.

, p. 1247 - 1250 (2012/03/26)

A series of pyrimidodiazepines was identified as potent Polo-like kinase 1 (PLK1) inhibitors. The synthesis and SAR are discussed. The lead compound 7 (RO3280) has potent inhibitory activity against PLK1, good selectivity against other kinases, and excell

POLO-LIKE KINASE INHIBITORS

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Page/Page column 158; 159-160, (2009/06/27)

Compounds of the following formula are provided for use with kinases, wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful

NOVEL COMPOUNDS

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Page/Page column 42, (2008/06/13)

There is provided a compound of formula (I): processes for the manufacture thereof, pharmaceutical compositions thereof and uses in therapy.

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