947-77-3

Basic information

• Product Name: Benzene, 1-methyl-2-(1-phenylethenyl)-
• CAS NO: 947-77-3
• Molecular Formula: C15H14
• Molecular Weight: 194.276
• Mol File: 947-77-3.mol
• Article Data: 38

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methyl-2-(1-phenylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methyl-2-(1-phenylethenyl)-(947-77-3)
• EPA Substance Registry System: Benzene, 1-methyl-2-(1-phenylethenyl)-(947-77-3)

Safety Data

• Hazardous Substances Data: 947-77-3(Hazardous Substances Data)

Upstream product

• 577-16-2 2-Methylacetophenone 
• 100-42-5 styrene 
• 90557-56-5 acetic acid-(N-nitroso-o-toluidide) 
• 98-86-2 acetophenone 
• 98-81-7 1-bromovinylbenzene 
• 16419-60-6 2-Methylphenylboronic acid 
• 66107-34-4 2-methylphenyl triflate 
• 95-48-7 ortho-cresol 
• 611-15-4 1-methyl-2-vinyl-benzene 
• 71-43-2 benzene 
• 100-58-3 phenylmagnesium bromide 
• 95-46-5 2-methylphenyl bromide 
• 4545-21-5 acetophenone p-toluenesulfonylhydrazone 
• 67-71-0 dimethylsulfone 

Downstream Products

• 61608-89-7 2,2'-Bis-(1-phenylethyl)-stilben 
• 131-58-8 2-Methylbenzophenone 
• 32341-92-7 1-(2-tolyl)-1-phenylethane 
• 72853-73-7 4-Methyl-5-phenylbenzanthracene-7,12-dione 
• 72853-74-8 5-o-Tolylbenzanthracene-7,12-dione 

Relevant articles and documents

Photoredox-Catalyzed α-Aminomethyl Carboxylation of Styrenes with Sodium Glycinates: Synthesis of γ-Amino Acids and γ-Lactams

A visible-light photoredox-catalyzed reductive α-aminomethyl carboxylation of styrenes with sodium glycinates and CO2 has been developed to synthesize a series of α,α-disubstituted γ-amino acids and γ-lactams with high efficiency and regioselectivity. Notably, CO2 released from the decarboxylation step can be reused for the subsequent carboxylation. Distinct from the previous reactions with the same type of substrates leading to simple decarboxylation and olefin hydroalkylation, this process involves additional CO2 sequestration, thus leading to olefin α-aminomethyl carboxylation. These findings not only provide new access to α,α-disubstituted γ-amino acids and γ-lactams but also serve as a proof of concept for CO2 reutilization in decarboxylation reactions.

Direct 1,2-Dicarbonylation of Alkenes towards 1,4-Diketones via Photocatalysis

1,4-Dicarbonyl compounds are intriguing motifs and versatile precursors in numerous pharmaceutical molecules and bioactive natural compounds. Direct incorporation of two carbonyl groups into a double bond at both ends is straightforward, but also challenging. Represented herein is the first example of 1,2-dicarbonylation of alkenes by photocatalysis. Key to success is that N(n-Bu)4+ not only associates with the alkyl anion to avoid protonation, but also activates the α-keto acid to undergo electrophilic addition. The α-keto acid is employed both for acyl generation and electrophilic addition. By tuning the reductive and electrophilic ability of the acyl precursor, unsymmetric 1,4-dicarbonylation is achieved for the first time. This metal-free, redox-neutral and regioselective 1,2-dicarbonylation of alkenes is executed by a photocatalyst for versatile substrates under extremely mild conditions and shows great potential in biomolecular and drug molecular derivatization.

Iron-Catalyzed Direct Julia-Type Olefination of Alcohols

Herein, we report an iron-catalyzed, convenient, and expedient strategy for the synthesis of styrene and naphthalene derivatives with the liberation of dihydrogen. The use of a catalyst derived from an earth-abundant metal provides a sustainable strategy to olefins. This method exhibits wide substrate scope (primary and secondary alcohols) functional group tolerance (amino, nitro, halo, alkoxy, thiomethoxy, and S- A nd N-heterocyclic compounds) that can be scaled up. The unprecedented synthesis of 1-methyl naphthalenes proceeds via tandem methenylation/double dehydrogenation. Mechanistic study shows that the cleavage of the C-H bond of alcohol is the rate-determining step.