947232-07-7Relevant articles and documents
Palladium-Catalyzed Domino Cyclization/Phosphorylation of gem-Dibromoolefins with P(O)H Compounds: Synthesis of Phosphorylated Heteroaromatics
Chen, Chen,Ding, Jie,Liu, Liying,Huang, Yujie,Zhu, Bolin
supporting information, p. 200 - 205 (2021/10/29)
We presented a palladium-catalyzed domino cyclization/phosphorylation of gem-dibromoolefins, which utilize H-phosphinates and secondary phosphine oxides as the phosphine sources, respectively. A variety of phosphorylated heteroaromatics were obtained in m
Copper-catalyzed synthesis of 1-(2-benzofuryl)-N-heteroarenes fromo-hydroxy-gem-(dibromovinyl)benzenes and N-heteroarenes
Rao, Maddali L. N.,Islam, Sk Shamim
supporting information, p. 9076 - 9080 (2021/11/04)
An efficient method for the synthesis of 1-(2-benzofuryl)-N-heteroarenes is developed fromo-hydroxy-gem-(dibromovinyl)benzenes and N-heteroarenes under copper-catalyzed tandem reaction conditions. This methodology displayed a broad substrate scope and high yields in the preparation of a variety of 1-(2-benzofuryl)-N-heteroarenes. Further, 1-(2-benzofuryl)-N-heteroarenes were also applied in the synthesis of polycyclic benzofuro-indolo-pyridine scaffolds under palladium-catalyzed dehydrogenative coupling conditions. Overall, the present tandem approach is general, synthetically advantageous and avoids air-sensitive reagents.
Intramolecular cross-coupling of gem-dibromoolefins: A mild approach to 2-bromo benzofused heterocycles
Newman, Stephen G.,Aureggi, Valentina,Bryan, Christopher S.,Lautens, Mark
supporting information; experimental part, p. 5236 - 5238 (2010/01/31)
Highly useful halogenated benzofurans and benzothiophenes are prepared from readily available gem-dibromoolefins using a mild, ligand-free copper catalyzed cross-coupling procedure.