947620-70-4

Basic information

• Product Name: 3-(2-chloro-6,7-dimethoxy-quinazolin-4-yl)-phenylamine
• Synonyms: 3-(2-chloro-6,7-dimethoxy-quinazolin-4-yl)-phenylamine
• CAS NO: 947620-70-4
• Molecular Weight: 315.759
• Mol File: 947620-70-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(2-chloro-6,7-dimethoxy-quinazolin-4-yl)-phenylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-chloro-6,7-dimethoxy-quinazolin-4-yl)-phenylamine(947620-70-4)
• EPA Substance Registry System: 3-(2-chloro-6,7-dimethoxy-quinazolin-4-yl)-phenylamine(947620-70-4)

Safety Data

• Hazardous Substances Data: 947620-70-4(Hazardous Substances Data)

Upstream product

• 1119772-74-5 t-Butyl [3-(2-chloro-6,7-dimethoxyquinazolin-4-yl)phenyl]carbamate 
• 27631-29-4 2-chloro-6,7-dimethoxy-3H-quinazolin-4-one 
• 30418-59-8 3-Aminophenylboronic acid 

Downstream Products

• 234751-30-5 [4-(3-aminophenyl)-6,7-dimethoxyquinazolin-2-yl]methylamine 
• 947620-69-1 methyl N-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid hydrate 
• 947620-48-6 methyl 4-[({3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl}amino)carbonyl]benzoate 

Relevant articles and documents

METHOD FOR PRODUCING QUINAZOLINE DERIVATIVE

[4-(3-aminophenyl)-6,7-dimethoxyquinazolin-2-yl]methylamine with a favorable yield and high purity can be produced by subjecting a compound represented by the following formula (I) to a step of reacting with methylamine and a step of deprotection if desired: wherein L represents a protective group of amino.

4-(3-BENZOYLAMINOPHENYL)-6,7-DIMETHOXY-2- METHYLAMINOQUINAZOLINE DERIVATIVE

A compound represented by the following formula (I), salt thereof, or hydrate thereof, can effectively relieve itch caused by atopic disease or the like: wherein R represents hydroxyl, C1-6 alkoxy optionally substituted with C1-6 alkoxy, or amino optionally substituted with C1-6 alkyl.