948020-54-0

Basic information

• Product Name: C₂₀H₁₈F₃N₃O₃
• Synonyms: C₂₀H₁₈F₃N₃O₃
• CAS NO: 948020-54-0
• Molecular Weight: 405.376
• Mol File: 948020-54-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₁₈F₃N₃O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₁₈F₃N₃O₃(948020-54-0)
• EPA Substance Registry System: C₂₀H₁₈F₃N₃O₃(948020-54-0)

Safety Data

• Hazardous Substances Data: 948020-54-0(Hazardous Substances Data)

Upstream product

• 22876-17-1 6-amino-1,3-benzoxazol-2-(3H)-one 
• 607354-69-8 1-(4-(trifluoromethyl)phenyl)piperidine-4-carboxyli c acid 

Relevant articles and documents

NIROGENOUS HETEROCYCLIC DERIVATIVES SUBSTITUTED WITH CYCLIC GROUPS

It was found out that the nitrogen-containing heterocyclic derivative represented by the formula (I) specifically binds to a receptor of NR1/NR2B, and is used as a NR2B receptor antagonist. A compound represented by: wherein Z is N or CR1, A1 is a nitrogen-containing aromatic monocyclic group which is optionally substituted, a nitrogen-containing aromatic fused cyclic group which is optionally substituted etc., A2 is an aromatic hydrocarbon cyclic group or an aromatic heterocyclic group, each optionally having a substituent, R1, R2, Ra, Rb, Rc and Rd are each independently hydrogen, hydroxy, etc., w is 2 or 3, t is 1 or 2, X is -(CR3R4)m-, -CO(CR3R4)n-, -CONR5(CR3R4)n- etc., m is an integer of 1 to 4, n is an integer of 0 to 4, R3 and R4 are each independently hydrogen, halogen, hydroxy etc., and R5 is hydrogen or lower alkyl, or a pharmaceutically acceptable salt, or a solvate thereof.