948054-25-9Relevant articles and documents
N-Nitrosulfonamides as Carbonic Anhydrase Inhibitors: A Promising Chemotype for Targeting Chagas Disease and Leishmaniasis
Bonardi, Alessandro,Vermelho, Alane Beatriz,Da Silva Cardoso, Veronica,De Souza Pereira, Mirian Claudia,Da Silva Lara, Leonardo,Selleri, Silvia,Gratteri, Paola,Supuran, Claudiu T.,Nocentini, Alessio
, p. 413 - 418 (2019)
Trypanosoma cruzi and Leishmania spp. are protozoa of the Trypanosomatidae family, respectively, responsible of the neglected tropical disorders (NTDs) Chagas disease and leishmaniasis. The present pharmacotherapy is often ineffective and exhibits serious
Synthesis of aromatic aminosulfonic acid nitroamides
Minksztym, Kazimierz
, p. 1819 - 1822 (2008/02/12)
Nitration of aromatic aminosulfonic acid primary amides to furnish the corresponding sulfononitroamides has been described for the first time. The conditions of nitration applied ensure chemoselective mononitration and prevent decomposition of the product. Synthesis of dabsyl nitroamide sodium salt, as a potential β-amyloid aggregation inhibitor is also reported. Georg Thieme Verlag Stuttgart.
