94825-44-2 Usage
Uses
Guanosine 5′-[γ-thio]triphosphate tetralithium salt has been used:as a component of lysis bufferin oocyte and mammalian cell patch-clamp experiments to keep the G proteins in a constantly active stateto couple with G- protein α, to study its effect on kinase activity
General Description
G-protein-activating GTP analog, which is more resistant to hydrolysis than GTP. Induces exocytosis in isolated mouse pancreatic acinar cells. Also reported to stimulate insulin release from pancreatic β-cells.
Biochem/physiol Actions
GTP-γ-S is a non-hydrolyzable GTP analog, known for its role as a G-protein activator. It has recently been shown to protect proteins from proteolytic degradation, stimulate GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization in vitro.
Check Digit Verification of cas no
The CAS Registry Mumber 94825-44-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,8,2 and 5 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 94825-44:
(7*9)+(6*4)+(5*8)+(4*2)+(3*5)+(2*4)+(1*4)=162
162 % 10 = 2
So 94825-44-2 is a valid CAS Registry Number.
