94915-46-5

Basic information

• Product Name: 4-(N,N-diethylamino)-2-phenyl-2-(2-pyridyl)butanenitrile
• Synonyms: 4-(N,N-diethylamino)-2-phenyl-2-(2-pyridyl)butanenitrile
• CAS NO: 94915-46-5
• Molecular Weight: 293.412
• Mol File: 94915-46-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(N,N-diethylamino)-2-phenyl-2-(2-pyridyl)butanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(N,N-diethylamino)-2-phenyl-2-(2-pyridyl)butanenitrile(94915-46-5)
• EPA Substance Registry System: 4-(N,N-diethylamino)-2-phenyl-2-(2-pyridyl)butanenitrile(94915-46-5)

Safety Data

• Hazardous Substances Data: 94915-46-5(Hazardous Substances Data)

Upstream product

• 5005-36-7 phenyl-pyridin-2-yl-acetonitrile 
• 100-35-6 2-(diethylamino)ethyl chloride 

Relevant articles and documents

Reaction of 4-(N,N-dimethylamino)-2-phenyl-2-(2-pyridyl)butanenitrile and related compounds with ethyl chloroformate; formation of indolizinium and quinolizinium chlorides

4-(N,N-Dialkylamino)-2-phenyl-2-(2-pyridyl)butanenitriles (10, 11 and 12) and 5-(N,N-dimethylamino)-2-phenyl-2-(2-pyridyl)pentanenitrile (13) react with ethyl chloroformate, via a cyclization-N-dealkylation process, to give indolizinium and quinolizinium salts (1 and 2). Compounds 1 and 2 are also obtained by reaction of the alcohol derivatives 14 and 15 with thionyl chloride. Reaction of 2-phenyl-2-(2-pyridyl)ethanenitrile (9) in the presence of potassium hydroxide in dimethyl sulfoxide, leading to [2-hydroxy-2-phenyl-2-(2-pyridyl)ethyl]methylsulfoxide (21), is also described.