949158-38-7Relevant articles and documents
Synthesis of 2′-O-[2-(N-methylcarbamoyl)ethyl]ribonucleosides using oxa-michael reaction and chemical and biological properties of oligonucleotide derivatives incorporating these modified ribonucleosides
Yamada, Takeshi,Okaniwa, Natsuki,Saneyoshi, Hisao,Ohkubo, Akihiro,Seio, Kohji,Nagata, Tetsuya,Aoki, Yoshitsugu,Takeda, Shin'ichi,Sekine, Mitsuo
, p. 3042 - 3053 (2011/06/21)
To develop oligonucleotides containing new 2′-O-modified ribonucleosides as nucleic acid drugs, we synthesized three types of ribonucleoside derivatives modified at the 2′-hydroxyl group with 2-(methoxycarbonyl)ethyl (MOCE), 2-(N-methylcarbamoyl)ethyl (MC