94943-13-2

Basic information

• Product Name: 1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one
• CAS NO: 94943-13-2
• Molecular Formula: C₁₈H₂₀O₅
• Molecular Weight: 316.3484
• Mol File: 94943-13-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 505.6°C at 760 mmHg
• Flash Point: 182.2°C
• Density: 1.18g/cm³
• Vapor Pressure: 4.79E-11mmHg at 25°C
• Refractive Index: 1.561
• CAS DataBase Reference: 1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one(94943-13-2)
• EPA Substance Registry System: 1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one(94943-13-2)

Safety Data

• Hazardous Substances Data: 94943-13-2(Hazardous Substances Data)

Usage

Description

1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one, a member of the chalcone family, is a chemical compound with the molecular formula C18H20O5. It is recognized for its antioxidant and anti-inflammatory properties, which contribute to its potential therapeutic and skincare applications.

Uses

Used in Pharmaceutical Industry:
1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one is used as a therapeutic agent for its potential health benefits, which include reducing the risk of chronic diseases. Its antioxidant and anti-inflammatory properties make it a promising candidate for further research and development in the pharmaceutical sector.
Used in Cosmetic Industry:
In the cosmetic industry, 1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one is used as an active ingredient for skincare products due to its potential to improve skin health. Its antioxidant properties may help protect the skin from environmental damage, while its anti-inflammatory effects could contribute to reducing signs of skin irritation and inflammation.
Further studies are necessary to fully understand the therapeutic potential and safety profile of 1-(2,4-dimethoxyphenyl)-2-hydroxy-3-(4-methoxyphenyl)propan-1-one, ensuring its effective and safe integration into pharmaceutical and cosmetic products.

Upstream product

• 77412-32-9 α-hydroxychalcone 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 18493-30-6 1-(2,4-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one 
• 123-11-5 4-methoxy-benzaldehyde 
• 829-20-9 2',4'-dimethoxyacetophenone 

Downstream Products

• 77412-32-9 α-hydroxychalcone 
• 117614-88-7 (+/-)-1-hydroxy-1-(2,4-dimethoxyphenyl)-3-(4-methoxyphenyl) propan-2-one 

Relevant articles and documents

α-HYDROXYDIHYDROCHALCONES AND RELATED 1,3-DIARYLPROPAN-2-ONES FROM XANTHOCERCIS ZAMBESIACA

Key Word Index-Xanthocercis zambesiaca; Leguminosae; 7,8-dioxyisoflavonoids; α-hydroxydihydrochalcones; 1,3-diarylpropan-2-ones.Abstract-In addition to some previously described 7,8-dioxy-isoflavonoids and 2-benzylbenzofuran-3(2H)-ones the heartwood of Xanthocercis zambesiaca has been shown to contain 7,8,3'-trihydroxy-4'-methoxyisoflavone.These are accompained by the novel α,3,4,4'-tetrahydroxy-2'-methoxydihydrochalcone and its 3-deoxy analogue, the latter of which presumably served as biogenetic precursor for the unique 1-hydroxy-3-(4-hydroxyphenyl)-1-(4-hydroxy-2-methoxyphenyl) propan-2-one and its 1-deoxy analogue.Such possible biosynthetic relationship was demonstrated by the facile in vitro transformations of the appropriate α-hydroxydihydrochalcone into the different 1,3-diarylpropan-2-ones.

A Novel α-Hydroxydihydrochalcone from the Heartwood of Pterocarpus angolensis D.C.: Absolute Configuration, Synthesis, Photochemical Transformations, and Conversion into α-Methyldeoxybenzoins

The absolute configuration of (αR)-α,2'-dihydroxy-4,4'-dimethoxydihydrochalcone from the heartwood of Pterocarpus angolensis D.C. is established.Its structure is substantiated by synthesis and by photochemical conversion of its α-O-tosyl derivative into an α-tosyloxymethyldeoxybenzoin and hence to the α-methyldeoxybenzoin analogue.The photochemical step also leads, amongst others, to α-hydroxymethyldeoxybenzoin, β-hydroxydihydrochalcone, and 2-benzylbenzofuran-3-one analogues depending on the conditions the photolysis.