950602-02-5Relevant articles and documents
Thiotetrazole alkynylacetanilides as potent and bioavailable non-nucleoside inhibitors of the HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases
Gagnon, Alexandre,Amad, Ma'an H.,Bonneau, Pierre R.,Coulombe, Rene,DeRoy, Patrick L.,Doyon, Louise,Duan, Jianmin,Garneau, Michel,Guse, Ingrid,Jakalian, Araz,Jolicoeur, Eric,Landry, Serge,Malenfant, Eric,Simoneau, Bruno,Yoakim, Christiane
, p. 4437 - 4441 (2007)
A series of aryl thiotetrazolylacetanilides were synthesized and found to be potent inhibitors of the HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases. The incorporation of an alkynyl fragment on the aniline provided inhibitors with ex
