95061-51-1 Usage
Description
(S)-(-)-2-HYDROXY-1,2,2-TRIPHENYLETHYL ACETATE, also known as (S)-2-Hydroxy-1,2,2-triphenylethyl Acetate, is a white to light yellow crystalline powder. It is a chiral compound with a specific stereochemistry, where the hydroxyl group is attached to the carbon atom in the S configuration. This unique structure makes it a valuable intermediate in the synthesis of various pharmaceutical compounds.
Uses
Used in Pharmaceutical Industry:
(S)-(-)-2-HYDROXY-1,2,2-TRIPHENYLETHYL ACETATE is used as a reactant in the synthesis of Lankacidin derivatives, which are 17-membered macrocyclic antibiotics. These antibiotics exhibit potent antimicrobial activity against a wide range of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). The unique macrocyclic structure of Lankacidin derivatives allows them to target specific bacterial proteins, leading to their potent and selective antimicrobial action.
Check Digit Verification of cas no
The CAS Registry Mumber 95061-51-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,0,6 and 1 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 95061-51:
(7*9)+(6*5)+(5*0)+(4*6)+(3*1)+(2*5)+(1*1)=131
131 % 10 = 1
So 95061-51-1 is a valid CAS Registry Number.
InChI:InChI=1/C22H20O3/c1-17(23)25-21(18-11-5-2-6-12-18)22(24,19-13-7-3-8-14-19)20-15-9-4-10-16-20/h2-16,21,24H,1H3/t21-/m0/s1
95061-51-1Relevant articles and documents
Total Synthesis of (-)-Disorazole C1
Lizzadro, Luca,Spie?, Oliver,Schinzer, Dieter
, p. 4543 - 4547 (2021/06/28)
Disorazoles represent a powerful class of highly potent antitubulin natural products isolated from myxobacteria. Herein, we describe a scalable and robust synthesis of (-)-disorazole C1 with high stereoselectivity, featuring quite simple reaction conditio
AN EFFICIENT LARGE SCALE PREPARATION OF (S)-1,1,2-TRIPHENYLETHANEDIOL 2-ACETATE
Millar, A.,Mulder, L. W.,Mennen, K. E.,Palmer, C. W.
, p. 173 - 180 (2007/10/03)
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Synthetic studies of the detoxin complex. I. Total synthesis of (-) detoxinine
Ewing,Harris,Bhat,Joullie
, p. 2421 - 2428 (2007/10/02)
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