951-98-4

Basic information

• Product Name: Propanoic acid, 2-oxo-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
• CAS NO: 951-98-4
• Molecular Formula: C13H22O3
• Molecular Weight: 226.316
• Mol File: 951-98-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-oxo-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-oxo-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester(951-98-4)
• EPA Substance Registry System: Propanoic acid, 2-oxo-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester(951-98-4)

Safety Data

• Hazardous Substances Data: 951-98-4(Hazardous Substances Data)

Upstream product

• 185915-25-7 lactic acid menthyl ester 
• 1188421-45-5 l-menthyl (+/-) 2-azidopropionate 
• 2216-51-5 (-)-menthol 
• 127-17-3 2-oxo-propionic acid 

Downstream Products

• 131053-11-7 (-)-menthyl N-acetyl-α,β-dehydroalaninate 
• 218897-94-0 1-Bromomethyl-2,3,4,9-tetrahydro-1H-β-carboline-1-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 218897-96-2 1,2,3,4,5,6-Hexahydro-azepino[4,5-b]indole-5-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 218897-95-1 1,2,3,6-Tetrahydro-azepino[4,5-b]indole-5-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 299188-59-3 (1R,2S,5R)-menthyl (S)-2-methoxy-2-(2-naphthyl)propionate 
• 439915-88-5 C₁₇H₂₉NO₅ 
• 299188-57-1 (1R,2S,5R)-(-)-menthyl (S)-2-hydroxy-2-(2-naphthyl)propionate 
• 250695-50-2 (-)-menthyl-4-(1,3-dioxolane-2-yl)-2-hydroxy-2-methylbutanoate 
• 218897-93-9 3-Bromo-2-oxo-propionic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 167391-17-5 l-menthyl (2S)-2-methyl-4-oxo-1,3-dioxine-2-carboxylate 
• 167391-18-6 l-menthyl (2R)-2,6-dimethyl-4-oxo-1,3-dioxine-2-carboxylate 

Relevant articles and documents

Absolute configuration of 2-hydroxy-2-(1-naphthyl)propionic acid as determined by the 1H NMR anisotropy method

Enantiopure 2-hydroxy-2-(1-naphthyl)propionic acid (+)-2 was prepared by the stereoselective Grignard reaction of 1-naphthylmagnesium bromide with (1R,3R,4S)-menthyl pyruvate 3 or (1R,3R,4S)-8-phenylmenthyl pyruvate 4, and the absolute configuration of acid (+)-2 was unambiguously determined to be S by the 1H NMR anisotropy method.

Method for producing optically active amino acid derivative

[PROBLEM TO BE SOLVED]: To provide a method for producing an optically active amino acid derivative which is suitable for the industrial production and handy. [SOLUTION]: The method for producing the amino acid derivative characterized by obtaining the amino acid derivative by reducing compound shown in general formula(1) with hydrogen under the existence of palladium carbon catalyst. (wherein R1 and R2 are the same or different and hydrogen atom, alkyl group, halogen, and amino group, -NHCOR4, -OR4 and -OCOR4; R3 is alkyl group, amino group, -NHCOR4,-OR4, -OCOR4; R4 is hydrogen atom, alkyl group, and aryl group. However, at least one of R1-R3 is above-mentioned - NHCOR4.)