95158-94-4Relevant articles and documents
Rate Enhancement in CAN-Promoted Pd(PPh3)2Cl2-Catalyzed Oxidative Cyclization: Synthesis of 2-Ketofuran-4-carboxylate Esters
Ruengsangtongkul, Sureeporn,Chaisan, Nattawadee,Thongsornkleeb, Charnsak,Tummatorn, Jumreang,Ruchirawat, Somsak
, p. 2514 - 2517 (2019/04/30)
Stoichiometric ceric ammonium nitrate (CAN) and a catalytic amount of Pd(PPh3)2Cl2 (5 mol %) can rapidly produce multisubstituted 2-ketofuran-4-carboxylate esters from 2-propargylic 1,3-ketoesters via oxidative O-cyclization reaction. Pd(PPh3)2Cl2 was found to be the crucial catalyst as its inclusion greatly enhanced the rate of the reaction and cleanly afforded the products within minutes. Over 30 substrates were successfully converted to the desired compounds in mostly moderate to good yields.
Indium-catalyzed synthesis of furans and pyrroles via cyclization of α-propargyl-β-keto esters
Tsuji, Hayato,Yamagata, Ken-Ichi,Ueda, Yasuyuki,Nakamura, Eiichi
supporting information; experimental part, p. 1015 - 1017 (2011/06/17)
In(OTf)3 or In(NTf2)3 effectively catalyze the cyclo-isomerization reaction of -propargyl - keto esters and their imine analogues to afford trisubstituted furans and pyrroles, respectively. Both terminal and internal alkyn
NEW FACILE SYNTHESIS OF SUBSTITUTED 2-BENZYLIDENEPYRROLIDINES BY THE ANIONIC CYCLIZATION OF δ-ALKYNYLAMINES
Tokuda, Masao,Fujita, Hirotake,Suginome, Hiroshi
, p. 5353 - 5356 (2007/10/02)
Treatment of δ-alkynylamines with butyllithium or lithium aluminum hydride brought about a facile anionic cyclization, giving high yields of the corresponding enamine pyrrolidines having an exo double bound.