952068-57-4

Basic information

• Product Name: Parishin E
• Synonyms: Parishin E;4-[(3,4-Dicarboxy-3-hydroxy-1-oxobutoxy)methyl]phenyl beta-D-glucopyranoside
• CAS NO: 952068-57-4
• Molecular Formula: C₁₉H₂₄O₁₃
• Molecular Weight: 460.38606
• Mol File: 952068-57-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 784.1±60.0 °C(Predicted)
• Appearance: /
• Density: 1.631±0.06 g/cm3(Predicted)
• PKA: 3.10±0.28(Predicted)
• CAS DataBase Reference: Parishin E(CAS DataBase Reference)
• NIST Chemistry Reference: Parishin E(952068-57-4)
• EPA Substance Registry System: Parishin E(952068-57-4)

Safety Data

• Hazardous Substances Data: 952068-57-4(Hazardous Substances Data)

Usage

Description

Parishin E, a natural active component derived from Gastrodia elata, is a promising candidate for the treatment of dementia. Its unique properties and bioactivity make it a valuable asset in the field of medicine.

Uses

Used in Pharmaceutical Industry:
Parishin E is used as a therapeutic agent for treating dementia due to its neuroprotective and cognitive-enhancing properties. It has the potential to improve memory and cognitive function in patients suffering from dementia-related disorders.
Used in Neurological Research:
Parishin E is utilized in neurological research as a compound of interest for studying the underlying mechanisms of dementia and exploring new avenues for treatment and prevention. Its bioactivity and potential to modulate various signaling pathways make it a valuable tool for understanding the complex nature of dementia and developing novel therapeutic strategies.

Upstream product

• 174972-80-6 parishin C 
• 62499-28-9 [3-[[[4-(beta-D-glucopyranosyloxy)phenyl]methoxy]carbonyl]-3-hydroxy-1,5-dioxo-1,5-pentanediyl] bis(oxymethylene-4,1-phenylene) bis-beta-D-glucopyranoside 

Relevant articles and documents

Transformation mechanisms of chemical ingredients in steaming process of gastrodia elata blume

To explore the transformation mechanisms of free gastrodin and combined gastrodin before and after steaming of Gastrodia elata (G. elata), a fresh G. elata sample was processed by the traditional steaming method prescribed by Chinese Pharmacopoeia (2015 version), and HPLC-ESI-TOF/MS method was used to identify the chemical composition in steamed and fresh G. elata. Finally, 25 components were identified in G. elata based on the characteristic fragments of the compounds and the changes of the 25 components of fresh and steamed G. elata were compared by the relative content. Hydrolysis experiments and enzymatic hydrolysis experiments of 10 monomer compounds simulating the G. elata steaming process were carried out for the first time. As a result, hydrolysis experiments proved that free gastrodin or p-hydroxybenzyl alcohol could be obtained by breaking ester bond or ether bond during the steaming process of G. elata. Enzymatic experiments showed that steaming played an important role in the protection of gastrodin, confirming the hypothesis that steaming can promote the conversion of chemical constituents of G. elata—inhibiting enzymatic degradation. This experiment clarified the scientific mechanism of the traditional steaming method of G. elata and provided reference for how to apply G. elata decoction to some extent.