95235-23-7

Basic information

• Product Name: Pyrrolo[2,1-b]quinazolin-9(1H)-one, 2,3-dihydro-3-(hydroxyphenylmethylene)-, (Z)-
• CAS NO: 95235-23-7
• Molecular Formula: C18H14N2O2
• Molecular Weight: 290.321
• Mol File: 95235-23-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Pyrrolo[2,1-b]quinazolin-9(1H)-one, 2,3-dihydro-3-(hydroxyphenylmethylene)-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolo[2,1-b]quinazolin-9(1H)-one, 2,3-dihydro-3-(hydroxyphenylmethylene)-, (Z)-(95235-23-7)
• EPA Substance Registry System: Pyrrolo[2,1-b]quinazolin-9(1H)-one, 2,3-dihydro-3-(hydroxyphenylmethylene)-, (Z)-(95235-23-7)

Safety Data

• Hazardous Substances Data: 95235-23-7(Hazardous Substances Data)

Upstream product

• 530-53-0 deoxyvasicinone 
• 98262-87-4 Benzoic acid [9-oxo-1,2-dihydro-9H-pyrrolo[2,1-b]quinazolin-(3Z)-ylidene]-phenyl-methyl ester 
• 98-88-4 benzoyl chloride 
• 93-97-0 benzoic acid anhydride 

Downstream Products

• 98262-87-4 Benzoic acid [9-oxo-1,2-dihydro-9H-pyrrolo[2,1-b]quinazolin-(3Z)-ylidene]-phenyl-methyl ester 

Relevant articles and documents

1-Acyldeoxyvasicinone salts as effective intermediate C- and N-acylating agents for alkaloids and amino acids

The reaction of deoxyvasicinone with acid chlorides of aliphatic (acetylbromide) and aromatic (benzoyl-, o-, p-methoxy-, p-nitrobenzoylchlorides) acids was studied. It was shown that 1-deoxyvasicinone salts were formed at room temperature; α-aroyloxymethylidenedeoxyvasicinones, in the presence of triethylamine at 80-85°C. It was found that acid chlorides cause 1-acyldeoxyvasicinone salts to transform into α-hydroxy-or α-aroyloxyarylidenedeoxyvasicinones, which indirectly confirmed their acylating properties. It was found that 1-acyldeoxyvasicinone salts were effective acylating agents for alkaloids (cytisine, 1,2-dihydrodeoxyvasicinone) and amino acids (glycine, β-alanine, α-aminobutyric acid) and can be used to acylate primary and secondary aliphatic and heterocyclic amines.