953091-29-7

Basic information

• Product Name: 4-Amino-3-fluoro-5-(trifluoromethyl)benzonitrile
• Synonyms: 4-Amino-3-fluoro-5-(trifluoromethyl)benzonitrile
• CAS NO: 953091-29-7
• Molecular Weight: 204.127
• Mol File: 953091-29-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-Amino-3-fluoro-5-(trifluoromethyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-3-fluoro-5-(trifluoromethyl)benzonitrile(953091-29-7)
• EPA Substance Registry System: 4-Amino-3-fluoro-5-(trifluoromethyl)benzonitrile(953091-29-7)

Safety Data

• Hazardous Substances Data: 953091-29-7(Hazardous Substances Data)

Upstream product

• 875664-46-3 4-bromo-2-fluoro-6-(trifluoromethyl)benzenamine 
• 143-33-9 sodium cyanide 
• 953091-28-6 2-fluoro-4-iodo-6-trifluoromethylphenylamine 
• 544-92-3 copper(I) cyanide 

Downstream Products

• 953091-31-1 4-aminomethyl-2-fluoro-6-trifluoromethylphenylamine 
• 1046447-04-4 4-chloro-3-fluoro-5-(trifluoromethyl)benzonitrile 
• 1046820-92-1 N-{2-[2-chloro-5-cyano-3-(trifluoromethyl)phenoxy]-1-cyano-1-methylethyl}-4-(pentafluorothio)benzamide 

Relevant articles and documents

FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES

Provided are compounds according to any of Formula (I-1) to (I-7), pharmaceutical compositions comprising at least one of said compounds, their use as a medicament, and their use in treating chronic hepatitis B virus (HBV) infection. Methods for preparing compounds according to any of Formula (I-1) to (I-7) are also provided.

NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, inflammatory disease of the joints, neuropathies, HIV-related neuropathy, nerve injury, neurodegeneration, stroke, urinary bladder hypersensitivity including urinary incontinence, cystitis, stomach duodenal ulcer, irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), fecal urgency, gastro-esophageal reflux disease (GERD), Crohn's disease, asthma, chronic obstructive pulmonary disease, cough, neurotic/allergic/inflammatory skin disease, psoriasis, pruritus, prurigo, irritation of skin, eye or mucous membrane, hyperacusis, tinnitus, vestibular hypersensitivity, episodic vertigo, cardiac diseases such as myocardial ischemia, hair growth-related disorders such as effluvium, alopecia, rhinitis, and pancreatitis.