95333-15-6

Basic information

• Product Name: Ethanone, 1-(4-benzofuranyl)- (9CI)
• Synonyms: Ethanone, 1-(4-benzofuranyl)- (9CI);1-(benzofuran-4-yl)ethanone
• CAS NO: 95333-15-6
• Molecular Formula: C10H8O2
• Molecular Weight: 160.16932
• Product Categories: ACETYLGROUP
• Mol File: 95333-15-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 256.3±13.0 °C(Predicted)
• Appearance: /
• Density: 1.161±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Ethanone, 1-(4-benzofuranyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(4-benzofuranyl)- (9CI)(95333-15-6)
• EPA Substance Registry System: Ethanone, 1-(4-benzofuranyl)- (9CI)(95333-15-6)

Safety Data

• Hazardous Substances Data: 95333-15-6(Hazardous Substances Data)

Upstream product

• 917-64-6 methyl magnesium iodide 
• 95333-17-8 benzofuran-4-carbonitrile 
• 866826-20-2 3-allyl-2-(2-chloroethoxy)acetophenone 
• 58621-39-9 2-acetyl-6-allylphenol 
• 53327-14-3 2'-allyloxyacetophenone 
• 118-93-4 o-hydroxyacetophenone 
• 121-71-1 3-Hydroxyacetophenone 
• 58621-37-7 2'-allyl-3'-hydroxyacetophenone 
• 58621-54-8 1-(3-(allyloxy)phenyl)ethan-1-one 
• 865760-01-6 2'-allyl-3'-(2''-chloroethoxy)acetophenone 
• 69227-65-2 4-nitro-benzofuran 
• 412336-07-3 4-aminobenzofuran 
• 111-34-2 -butyl vinyl ether 
• 177734-79-1 benzofuran-4-yl trifluoromethanesulfonate 

Relevant articles and documents

NOVEL TRICYCLIC CALCIUM SENSING RECEPTOR ANTAGONISTS

Novel tricyclic compounds of Formula (I) and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing osteoporosis and similar conditions. The compounds are effective as calcium sensing receptor antagonists. Pharmaceutical compositions and methods of treatment are also included.

Synthesis of certain benzoheterocyclic com pounds from 2- hydroxyacetophenone via cyclization and ring-closing metathesis

Syn the sis of some benzoheterocyclic compounds like substituted benzofurans, 4-methyl-2H-chromenes and 3,4-dihydro-2H-benzo[e]oxepin-5-ones from 2-hydroxyacetophenone via base in duced cyclization and ring-closingme tath e sis (RCM) is described.

CONFORMATIONAL ANALYSIS OF ORGANIC CARBONYL COMPOUNDS. PART 4. A (1)H AND (13)C NUCLEAR MAGNETIC RESONANCE STUDY OF FORMYL AND ACETYL DERIVATIVES OF BENZOFURAN

A conformational study of formyl and acetyl derivatives of benzofuran provides evidence that in the case of 2- and 7-derivatives the E,Z-conformational mixture is solvent dependent, the Z-form prevailing in solvents with higher polarity.The presence of the same substituents in the 3- and 4-position gives compounds with predominantly Z-conformation and no change is caused by solvents.These results show an interestingly different behaviour by carbonyl derivatives of benzofuran with respect to the same benzothiophene derivatives.The conformational analysis was carried out by the n.m.r. method by employing (1)H and (13)C chemical shifts, long-range proton-proton coupling constants, and lanthanide-induced shifts (LIS) simulation.For the derivatives substituted in position 7, the LIS method is not a suitable approach for the determination of the conformer populations since, in solution, a chelate is formed where bonding of Eu to the oxygen atoms of the carbonyl and of the heterocyclic ring stabilizes the Z-form.A quantitative approach for determining the relative conformer populations of benzofuran-7-carbaldehyde was set up by statistical manipulation of long-range proton-proton coupling constants, proton chemical shifts, and the classical of dielectrics.