95337-70-5 Usage
General Description
4-(2,5-DIMETHYL-1H-PYRROL-1-YL)BENZALDEHYDE, also known as Tropinone, is a chemical compound with a molecular formula of C14H15NO. It is a white to off-white powder that is used in the synthesis of organic compounds and pharmaceuticals. Tropinone is a key intermediate in the production of atropine, a medication used to treat certain types of nerve agent and pesticide poisonings, as well as to reduce salivation and respiratory secretions during surgery. It is also used in the synthesis of other drugs with anticholinergic effects and as a precursor for the production of cocaine. Tropinone has a wide range of applications in the pharmaceutical and chemical industries and is an important building block for the synthesis of various biologically active molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 95337-70-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,3,3 and 7 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 95337-70:
(7*9)+(6*5)+(5*3)+(4*3)+(3*7)+(2*7)+(1*0)=155
155 % 10 = 5
So 95337-70-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H13NO/c1-10-3-4-11(2)14(10)13-7-5-12(9-15)6-8-13/h3-9H,1-2H3
95337-70-5Relevant articles and documents
One-pot synthesis of: N -substituted pyrroles from nitro compounds and 2,5-hexadione over a heterogeneous cobalt catalyst
Gong, Zheng,Lei, Yu,Zhou, Peng,Zhang, Zehui
, p. 10613 - 10618 (2017/10/05)
In this study, the one-pot heterocyclization of nitro compounds with 2,5-hexadione was studied for the synthesis of N-substituted pyrroles via a Paal-Knorr condensation process. The heterogeneous cobalt-nitrogen catalyst (Co-Nx/C-800-AT) was found to be active for this reaction with formic acid. Formic acid served as a hydrogen donor for the transfer hydrogenation, and also acted as an acid catalyst. More importantly, this method was tolerant of other functional groups, and hence various N-substituted pyrroles were produced with good to excellent yields. The Co-Nx/C-800-AT catalyst was highly stable, and could be reused several times without loss of its catalytic activity.
